Clinical effectiveness of Invisalign® orthodontic treatment: a systematic review.

Papadimitriou, Aikaterini; Mousoulea, Sophia; Gkantidis, Nikolaos; Kloukos, Dimitrios (2018). Clinical effectiveness of Invisalign® orthodontic treatment: a systematic review. Progress in orthodontics, 19(1), p. 37. Springer 10.1186/s40510-018-0235-z

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BACKGROUND Aim was to systematically search the literature and assess the available evidence regarding the clinical effectiveness of the Invisalign® system. METHODS Electronic database searches of published and unpublished literature were performed. The reference lists of all eligible articles were examined for additional studies. Reporting of this review was based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. RESULTS Three RCTs, 8 prospective, and 11 retrospective studies were included. In general, the level of evidence was moderate and the risk of bias ranged from low to high, given the low risk of bias in included RCTs and the moderate (n = 13) or high (n = 6) risk of the other studies. The lack of standardized protocols and the high amount of clinical and methodological heterogeneity across the studies precluded a valid interpretation of the actual results through pooled estimates. However, there was substantial consistency among studies that the Invisalign® system is a viable alternative to conventional orthodontic therapy in the correction of mild to moderate malocclusions in non-growing patients that do not require extraction. Moreover, Invisalign® aligners can predictably level, tip, and derotate teeth (except for cuspids and premolars). On the other hand, limited efficacy was identified in arch expansion through bodily tooth movement, extraction space closure, corrections of occlusal contacts, and larger antero-posterior and vertical discrepancies. CONCLUSIONS Although this review included a considerable number of studies, no clear clinical recommendations can be made, based on solid scientific evidence, apart from non-extraction treatment of mild to moderate malocclusions in non-growing patients. Results should be interpreted with caution due to the high heterogeneity.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > School of Dental Medicine > Department of Orthodontics

UniBE Contributor:

Gkantidis, Nikolaos and Kloukos, Dimitrios

Subjects:

600 Technology > 610 Medicine & health

ISSN:

2196-1042

Publisher:

Springer

Language:

English

Submitter:

Renate Imhof-Etter

Date Deposited:

28 Mar 2019 11:19

Last Modified:

31 Mar 2019 03:37

Publisher DOI:

10.1186/s40510-018-0235-z

PubMed ID:

30264270

Uncontrolled Keywords:

Aligner Clinical efficiency Invisalign Orthodontics

BORIS DOI:

10.7892/boris.124115

URI:

https://boris.unibe.ch/id/eprint/124115

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