Theoretical principles of capillary electromigration methods

Thormann, Wolfgang (2018). Theoretical principles of capillary electromigration methods. In: Poole, Colin F. (ed.) Capillary Electromigration Separation Methods (pp. 21-44). Elsevier 10.1016/B978-0-12-809375-7.00002-2

[img] Text
R057-Poole book chapter on CE theory.pdf - Published Version
Restricted to registered users only
Available under License Publisher holds Copyright.

Download (1MB) | Request a copy

During the past 50 years, electrophoretic separations and analyses in capillaries and microchannels emerged as techniques which provide high-resolution separations with on-column and/or end-column sample detection while requiring only small amounts of sample and reagents. Techniques developed include capillary zone electrophoresis, capillary isotachophoresis, capillary isoelectric focusing, capillary gel electrophoresis, affinity capillary electrophoresis, electrokinetic capillary chromatography and capillary electrochromatography. This chapter provides the theoretical principles of capillary electromigration methods, namely short descriptions of electrokinetic phenomena, efficiency of analyte transport, the concept of mobility, dispersion and focusing of analytes, the regulating principle, the occurrence of system peaks, dynamic computer simulations of capillary electrophoresis and other computer models to predict transport and separation in capillary electrophoresis.

Item Type:

Book Section (Book Chapter)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases > Laboratory for Clinical Pharmacology

UniBE Contributor:

Thormann, Wolfgang

Publisher:

Elsevier

Language:

English

Submitter:

Wolfgang Thormann

Date Deposited:

26 Feb 2019 14:39

Last Modified:

22 Dec 2019 02:31

Publisher DOI:

10.1016/B978-0-12-809375-7.00002-2

BORIS DOI:

10.7892/boris.124603

URI:

https://boris.unibe.ch/id/eprint/124603

Actions (login required)

Edit item Edit item
Provide Feedback