Paternal exposure to antirheumatic drugs-What physicians should know: Review of the literature.

Micu, M C; Ostensen, M; Villiger, Peter; Micu, R; Ionescu, R (2018). Paternal exposure to antirheumatic drugs-What physicians should know: Review of the literature. Seminars in arthritis and rheumatism, 48(2), pp. 343-355. Elsevier: 12 months 10.1016/j.semarthrit.2018.01.006

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Reproduction capacity and long-term preserved hormonal function are important aspects with big impacts on patients' quality of life. Updated information on the interaction between drug therapy and reproductive function is essential when discussing family planning with patients. Currently, limited data is published regarding paternal exposure to different medications. Thus, it may be a challenge for the practitioner to choose the right therapy for a young male patient. Therefore we reviewed the literature, for effects of antirheumatic drugs on male gonadal function with a focus on spermatogenesis and offspring.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Rheumatology, Clinical Immunology and Allergology

UniBE Contributor:

Villiger, Peter Matthias

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0049-0172

Publisher:

Elsevier: 12 months

Language:

English

Submitter:

Burkhard Möller

Date Deposited:

17 Jul 2019 14:35

Last Modified:

05 Dec 2022 15:25

Publisher DOI:

10.1016/j.semarthrit.2018.01.006

PubMed ID:

29502800

Uncontrolled Keywords:

Antirheumatic drugs Biologic therapy DMARDs Fertility Offspring outcome Paternal exposure Pregnancy outcome Sperm parameters

BORIS DOI:

10.7892/boris.125129

URI:

https://boris.unibe.ch/id/eprint/125129

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