Association of Oral-Health Related Quality of Life and General Health Assessment in Patients with Rheumatoid Arthritis.

Tristiu, Roxana; Vesa, Stefan; Dumitru, Raluca B; Arweiler, Nicole B; Cosgarea, Rodica M; Lascu, Liana; Rednic, Simona; Eick, Sigrun; Sculean, Anton; Cosgarea, Raluca (2018). Association of Oral-Health Related Quality of Life and General Health Assessment in Patients with Rheumatoid Arthritis. Oral health & preventive dentistry, 16(3), pp. 271-280. Quintessenz Verlags-GmbH 10.3290/j.ohpd.a39912

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To determine the impact of oral health related quality of life (OHRQoL) on general health in patients suffering from rheumatoid arthritis (RA).


Ninety-one patients with RA (mean age 52.82 ± 11 years, 75.82% female, 20.87% smokers) and 30 systemically healthy patients (control) were evaluated for their OHRQoL by means of the Geriatric Oral Health Assessment Index (GOHAI) and the Oral Health Impact Profile (OHIP)-14 questionnaires. Self-perceived RA status was assessed using the Routine Assessment of Patient Index Data 3 (RAPID3).


The mean SC-GOHAI score was 3.69 ± 2.47 for RA subjects and 1.36 ± 2.69 in the control group. Statistically significant differences were seen between RA and control groups (p < 0.05). RA patients with and without periodontitis (PA) exhibited similar SC-GOHAI (Simple Count GOHAI) scores (p = 0.980). No statistically significant differences were observed between any of the groups, either for the OHIP 14-extent or for the OHIP 14-prevalence. RAPID3 scores showed that the majority of the RA patients (65.93%) had high disease severity (RAPID3 >12, mean RAPID3 score 14.39 ± 5.14). Statistically significantly higher values were recorded for general health assessment (PTGE, p = 0.009) and fatigue (FT, p = 0.004) in RA with PA as compared to those without. SC-GOHAI with values between 5 and 8 was statistically significantly associated with high severity health impairment (RAPID3 >12, p = 0.014, OR: 8.64).


Within their limits, the present findings indicate that: a) moderate OHRQoL as assessed by GOHAI may contribute to high severity impairment of health in RA patients, and b) the GOHAI questionnaire may represent a more adequate tool than OHIP-14 for assessing OHRQoL in patients suffering from RA.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > School of Dental Medicine > Department of Periodontology
04 Faculty of Medicine > School of Dental Medicine > Periodontics Research

UniBE Contributor:

Eick, Sigrun, Sculean, Anton


600 Technology > 610 Medicine & health




Quintessenz Verlags-GmbH




Doris Burri

Date Deposited:

26 Jun 2019 12:20

Last Modified:

05 Dec 2022 15:25

Publisher DOI:


PubMed ID:


Uncontrolled Keywords:

general health oral-health related quality of life periodontitis rheumatoid arthritis




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