Evaluation of the frequency of putative prostate cancer stem cells in primary and metastatic prostate cancer

Eaton, Colby L; Colombel, Marc; van der Pluijm, Gabri; Cecchini, Marco; Wetterwald, Antoinette; Lippitt, Jenny; Rehman, Ishtiaq; Hamdy, Freddie; Thalman, George (2010). Evaluation of the frequency of putative prostate cancer stem cells in primary and metastatic prostate cancer. Prostate, 70(8), pp. 875-82. Hoboken, N.J.: Wiley-Blackwell 10.1002/pros.21121

Full text not available from this repository. (Request a copy)

Tumour cells with a stem cell-like phenotype have recently been identified in prostate tumors and it has been suggested that this population may be responsible for the diversity of cell types within tumors and also for the initiation of metastases. These cells carry a number of defined markers: they are cd133 and cd44+ve and express high levels of alpha2beta1 integrin. In this study we have, for the first time, assessed matched primary and bone marrow biopsies from prostate cancer patients for the distribution of cells carrying these and a number of other putative stem cell markers.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Urology

UniBE Contributor:

Cecchini, Marco Giovanni

ISSN:

0270-4137

Publisher:

Wiley-Blackwell

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:10

Last Modified:

04 May 2014 23:05

Publisher DOI:

10.1002/pros.21121

PubMed ID:

20127735

Web of Science ID:

000278240600008

URI:

https://boris.unibe.ch/id/eprint/1254 (FactScience: 202408)

Actions (login required)

Edit item Edit item
Provide Feedback