Triscott, Joanna; Rubin, Mark A. (2018). Prostate Power Play: Does Accelerate -Deficient Cancer Progression? Cancer discovery, 8(6), pp. 682-685. American Association for Cancer Research 10.1158/2159-8290.CD-18-0369
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PI3K pathway alterations are frequently recurrent in metastatic prostate cancer and are associated with the development of currently incurable castration-resistant disease. Candidate inhibitors that target single PI3K pathway members lack efficacy as demonstrated in multiple clinical trials. In this issue, Pearson and colleagues examine the functional importance of co-occurring and aberrations using a novel mouse model and demonstrate a synergistic acceleration of tumorigenesis that may be responsible for metastatic prostate cancer. .
Item Type: |
Journal Article (Further Contribution) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Präzisionsonkologie 04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Präzisionsonkologie 04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) |
UniBE Contributor: |
Triscott, Joanna Catherine Caprio, Rubin, Mark Andrew |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
2159-8290 |
Publisher: |
American Association for Cancer Research |
Language: |
English |
Submitter: |
Marla Rittiner |
Date Deposited: |
17 Dec 2019 13:06 |
Last Modified: |
05 Dec 2022 15:25 |
Publisher DOI: |
10.1158/2159-8290.CD-18-0369 |
PubMed ID: |
29858226 |
BORIS DOI: |
10.7892/boris.125522 |
URI: |
https://boris.unibe.ch/id/eprint/125522 |
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