Mycobacterium decipiens sp. nov., a new species closely related to the Mycobacterium tuberculosis complex.

Brown-Elliott, Barbara A; Simmer, Patricia J; Trovato, Alberto; Hyle, Emily P; Droz, Sara Christine; Buckwalter, Seanne P; Borroni, Emanuele; Branda, John A; Iana, Elkina; Mariottini, Alessandro; Nelson, Jameelah; Matteelli, Alberto; Toney, Nadege C; Scarparo, Claudio; de Man, Tom J B; Vasireddy, Ravikiran; Gandhi, Rajesh T; Wengenack, Nancy L; Cirillo, Daniela M; Wallace, Richard J; ... (2018). Mycobacterium decipiens sp. nov., a new species closely related to the Mycobacterium tuberculosis complex. International journal of systematic and evolutionary microbiology, 68(11), pp. 3557-3562. Society for General Microbiology SGM 10.1099/ijsem.0.003031

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Two mycobacterial strains with close similarity to the Mycobacterium tuberculosis complex (MTBC) were isolated from cutaneous lesions of patients in the USA and Italy. At the phenotypic level, similarities to the MTBC included slow growth rate, rough morphotype of the unpigmented colonies and nearly identical high-performance liquid chromatography profiles of mycolic acids. In contrast to the MTBC, the strains were niacin- and nitrate-negative, and catalase-positive both at 68 °C and in semi-quantitative tests. The clinical isolates were more closely related to M. tuberculosis than to any other known mycobacterium and scored positive with commercial DNA probes (Hologic AccuProbe M. tuberculosis). Both average nucleotide identity and genome-to-genome distance suggested the strains are different from the MTBC. Therefore, given the distinguishing phenotypic and genomic-scale differences, we submit that the strains belong to a new species we have named Mycobacteriumdecipiens with type strain TBL 1200985 (=ATCC TSD-117=DSM 105360).

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases > General Bacteriology

UniBE Contributor:

Droz, Sara Christine

ISSN:

1466-5026

Publisher:

Society for General Microbiology SGM

Language:

English

Submitter:

Siegfried Hektor Hapfelmeier-Balmer

Date Deposited:

01 Apr 2019 12:41

Last Modified:

23 Oct 2019 04:38

Publisher DOI:

10.1099/ijsem.0.003031

PubMed ID:

30204586

Uncontrolled Keywords:

Mycobacterium decipiens Mycobacterium tuberculosis complex average nucleotide identity whole genome sequencing

BORIS DOI:

10.7892/boris.125735

URI:

https://boris.unibe.ch/id/eprint/125735

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