Surgical staging in endometrial cancer.

Gasparri, Maria Luisa; Caserta, Donatella; Benedetti Panici, Pierluigi; Papadia, Andrea; Mueller, Michael (2019). Surgical staging in endometrial cancer. Journal of cancer research and clinical oncology, 145(1), pp. 213-221. Springer 10.1007/s00432-018-2792-4

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In several malignancies, it has been demonstrated that the lymph nodal status is the most important pathologic factor affecting prognosis and giving the indication to further adjuvant treatment. The surgical assessment of the lymph nodal status in endometrial cancer is debated since 30 years. Recently, the sentinel lymph node mapping is rapidly gaining clinical acceptance in endometrial cancer. The adoption of Indocyanine Green as a safe and user friendly tracer for sentinel lymph node mapping increased the speed to which this procedure is getting applied in clinical practice. As a consequence of this rapid growth, several fundamental questions have been raised and are still debatable. In this manuscript, we discuss the importance of a known pathological lymph nodal status, the technique of the sentinel lymph node mapping with the reported false negative rates and detection rates according to the different tracers adopted, and the clinical scenarios in which a sentinel lymph node mapping could be employed.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Gynaecology

UniBE Contributor:

Papadia, Andrea and Mueller, Michael

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1432-1335

Publisher:

Springer

Language:

English

Submitter:

Monika Zehr

Date Deposited:

08 Mar 2019 14:54

Last Modified:

21 Nov 2019 04:48

Publisher DOI:

10.1007/s00432-018-2792-4

PubMed ID:

30460411

Uncontrolled Keywords:

Endometrial cancer Fluorescence Indocyanine green Laparoscopy Sentinel lymph node mapping

BORIS DOI:

10.7892/boris.125852

URI:

https://boris.unibe.ch/id/eprint/125852

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