Estimation of the diagnostic accuracy of clinical parameters for monitoring peri-implantitis progression: An experimental canine study.

Monje, Alberto; Insua, Angel; Rakic, Mia; Nart, Jose; Moyano-Cuevas, Jose Luis; Wang, Hom-Lay (2018). Estimation of the diagnostic accuracy of clinical parameters for monitoring peri-implantitis progression: An experimental canine study. Journal of periodontology, 89(12), pp. 1442-1451. American Academy of Periodontology 10.1002/JPER.18-0081

[img] Text
Monje_et_al-2018-Journal_of_Periodontology.pdf - Published Version
Restricted to registered users only
Available under License Publisher holds Copyright.

Download (668kB)

BACKGROUND

Lack of consensus on the clinical parameters of peri-implantitis may complicate accurate diagnosis of the disorder. Furthermore, the lack of reliable estimates of the diagnostic capacity of the clinical endpoints precludes the definition of an effective treatment protocol for peri-implantitis. The present canine study assesses the diagnostic accuracy of the clinical parameters for monitoring the peri-implant tissues in a controlled ligature-induced peri-implantitis model followed by a spontaneous progression phase.

METHODS

Six beagle dogs were followed-up on during three episodes of ligature-induced peri-implantitis and a further episode of spontaneous progression. Probing depth (PD), bleeding on probing (BOP), mucosal recession (MR), and suppuration (SUP) were recorded at four sites per implant and at four study timepoints. Moreover, the implant mucosal index (IMI) was calculated at implant level. Marginal bone loss (MBL) was determined using computed tomography at four sites per implant. A linear regression model was used to estimate clinical and radiological parameters during peri-implantitis progression.

RESULTS

Progressive peri-implant bone loss is characterized by an increase in PD, more profuse BOP, MR, and SUP in advanced cases (p < 0.001). However, even in the presence of severe bone loss, SUP was not a common finding, with an incidence of approximately 10% at the last timepoint. These clinical parameters were significantly correlated to MBL at most of the timepoints. The IMI, in turn, showed a positive correlation to MBL and the peri-implant inflammatory signs (r = 0.39; p < 0.001), with a tendency to exhibit higher scores during ligature-induced peri-implantitis, followed by a slight decrease during the spontaneous progression period.

CONCLUSION

The clinical features of peri-implantitis and spontaneous progression of the disorder may facilitate an accurate monitoring of peri-implant pathologic bone loss.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > School of Dental Medicine > Research

UniBE Contributor:

Monje, Alberto

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0022-3492

Publisher:

American Academy of Periodontology

Language:

English

Submitter:

Caroline Balz

Date Deposited:

11 Apr 2019 17:16

Last Modified:

05 Dec 2022 15:26

Publisher DOI:

10.1002/JPER.18-0081

PubMed ID:

30014465

Uncontrolled Keywords:

dental implants diagnosis implant stability peri-implant mucositis peri-implantitis

BORIS DOI:

10.7892/boris.126158

URI:

https://boris.unibe.ch/id/eprint/126158

Actions (login required)

Edit item Edit item
Provide Feedback