Colostral transmission of BTV-8 antibodies from dairy cows six years after vaccination.

Ayrle, Hannah; Mevissen, Meike; Kaske, Martin; Vögtlin, Andrea; Fricker, Raffael; Hoffmann, Bernd; Büttner, Mathias; Marinovic, Zlatko; Walkenhorst, Michael (2018). Colostral transmission of BTV-8 antibodies from dairy cows six years after vaccination. Vaccine, 36(39), pp. 5807-5810. Elsevier 10.1016/j.vaccine.2018.08.015

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Bluetongue virus (BTV) antibodies were analysed in 27 Swiss calves born in 2016 at the age of 16-19 days using competitive enzyme-linked-immunosorbent-assay (cELISA) and virus neutralization test (VNT) (animal trial permission number: 75684). Obligatory documentation proved that 15 of 27 dams were BTV-8 vaccinated once or three times in 2008-2010. The offsprings of the non-vaccinated dams were seronegative. Two of three calves and 11 of 12 calves descending from dams who had been vaccinated one or three times, respectively, had BTV specific serum antibodies. As Switzerland is considered BTV-free from 2010 to 2016, it is likely that BTV-8 antibodies were transferred via colostrum. Furthermore, we confirmed neutralizing cross-reactivity of BTV-8 with BTV-4 antibodies as 5 samples positive for BTV-8 were also reactive with BTV-4 antibodies.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Research Foci > Host-Pathogen Interaction
05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH) > Veterinary Pharmacology and Toxicology
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP)
05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH)

UniBE Contributor:

Ayrle, Hannah and Mevissen, Meike

Subjects:

600 Technology > 630 Agriculture
500 Science > 570 Life sciences; biology

ISSN:

0264-410X

Publisher:

Elsevier

Language:

English

Submitter:

Achim Braun Parham

Date Deposited:

21 May 2019 15:06

Last Modified:

21 May 2019 15:06

Publisher DOI:

10.1016/j.vaccine.2018.08.015

PubMed ID:

30100070

Uncontrolled Keywords:

Bluetongue virus Cattle Maternal antibodies Vaccination

BORIS DOI:

10.7892/boris.127511

URI:

https://boris.unibe.ch/id/eprint/127511

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