Comparison and Validation of Three Fumigation Methods to Inactivate Foot-and-Mouth Disease Virus

Kümin, Daniel; Gsell Albert, Monika; Summermatter, Kathrin (2018). Comparison and Validation of Three Fumigation Methods to Inactivate Foot-and-Mouth Disease Virus. Applied biosafety, 23(2), pp. 70-76. Sage 10.1177/1535676018771982

Full text not available from this repository.

Foot-and-mouth disease virus (FMDV) is a highly pathogenic and transmissible disease of cloven-hoofed animals with outbreaks having severe impact on livestock production. FMDV is generally studied in high- to maximum-containment laboratories to prohibit the virus from escaping into the environment. Formaldehyde is still the method of choice for fumigation of rooms and HEPA filters at FMDV facilities. However, formaldehyde, having been shown to be carcinogenic, should ideally be replaced by other, less hazardous methods. Here we show validation results for two different hydrogen peroxide fumigation methods and compare these to formaldehyde fumigation. The results identify hydrogen peroxide as a suitable alternative to formaldehyde fumigation.

Item Type:	Journal Article (Review Article)
Division/Institute:	05 Veterinary Medicine > Research Foci > Host-Pathogen Interaction 05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Virology and Immunology 05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP)
UniBE Contributor:	Kümin, Daniel, Gsell-Albert, Monika, Summermatter, Kathrin
Subjects:	500 Science > 570 Life sciences; biology 600 Technology > 630 Agriculture
ISSN:	1535-6760
Publisher:	Sage
Language:	English
Submitter:	Pamela Schumacher
Date Deposited:	20 May 2019 15:15
Last Modified:	02 Mar 2023 23:31
Publisher DOI:	10.1177/1535676018771982
URI:	https://boris.unibe.ch/id/eprint/127527