Comparison and Validation of Three Fumigation Methods to Inactivate Foot-and-Mouth Disease Virus

Kümin, Daniel; Gsell Albert, Monika; Summermatter, Kathrin (2018). Comparison and Validation of Three Fumigation Methods to Inactivate Foot-and-Mouth Disease Virus. Applied biosafety, 23(2), pp. 70-76. Sage 10.1177/1535676018771982

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Foot-and-mouth disease virus (FMDV) is a highly pathogenic and transmissible disease of cloven-hoofed animals with outbreaks having severe impact on livestock production. FMDV is generally studied in high- to maximum-containment laboratories to prohibit the virus from escaping into the environment. Formaldehyde is still the method of choice for fumigation of rooms and HEPA filters at FMDV facilities. However, formaldehyde, having been shown to be carcinogenic, should ideally be replaced by other, less hazardous methods. Here we show validation results for two different hydrogen peroxide fumigation methods and compare these to formaldehyde fumigation. The results identify hydrogen peroxide as a suitable alternative to formaldehyde fumigation.

Item Type:

Journal Article (Review Article)

Division/Institute:

05 Veterinary Medicine > Research Foci > Host-Pathogen Interaction
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Virology and Immunology
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP)

UniBE Contributor:

Kümin, Daniel; Gsell Albert, Monika and Summermatter, Kathrin

Subjects:

500 Science > 570 Life sciences; biology
600 Technology > 630 Agriculture

ISSN:

1535-6760

Publisher:

Sage

Language:

English

Submitter:

Achim Braun Parham

Date Deposited:

20 May 2019 15:15

Last Modified:

20 May 2019 15:15

Publisher DOI:

10.1177/1535676018771982

URI:

https://boris.unibe.ch/id/eprint/127527

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