Optimising cost-effectiveness of freedom from disease surveillance-Bluetongue Virus Serotype 8 as an example.

Rüegg, Simon R; Welby, Sarah; Yassin, Hurria; Van der Stede, Yves; Nafzger, Rebekka; Saatkamp, Helmut; Schüpbach, Gertraud Irene; Stärk, Katharina D C (2018). Optimising cost-effectiveness of freedom from disease surveillance-Bluetongue Virus Serotype 8 as an example. Preventive veterinary medicine, 160, pp. 145-154. Elsevier 10.1016/j.prevetmed.2018.02.009

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The aim of this study was to propose a procedure for optimising the cost-effectiveness of vector borne disease surveillance using a scenario tree model and cost-effectiveness analysis. The surveillance systems for Bluetongue Virus serotype 8 (BTV-8) implemented in Switzerland and Belgium were used as examples. In twenty four different, simulated population structures, passive surveillance and five designs of active surveillance were investigated. The influence of surveillance system design and parameters such as farmer disease awareness, veterinary disease awareness, herd and within-herd design prevalence on the overall surveillance system sensitivity were assessed. Furthermore, the cost-effectiveness of mandatory and voluntary vaccination regimes in relation to disease surveillance was investigated. Under the assumption that BTV-8 manifests clinically, freedom from disease in a population can be established with almost certainty over the period of one year using clinical surveillance alone. Additional investment in active surveillance would therefore economically only be justified, if no clinical manifestation is suspected or other surveillance objectives are to be provided such as early detection. The best cost-effectiveness is obtained by sampling more herds rather than more animals within a herd. Mandatory vaccination reduces the cost of surveillance by 0.26 € per vaccine and voluntary vaccination only marginally reduces the cost of risk-based surveillance, by reducing the population at risk. Finally, in populations with predominantly dairy cattle, bulk-tank milk testing is the method of choice to actively demonstrate freedom from disease.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Research Foci > Veterinary Public Health / Herd Health Management
05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH) > Veterinary Public Health Institute
05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH)

UniBE Contributor:

Schüpbach, Gertraud Irene

Subjects:

600 Technology > 630 Agriculture

ISSN:

0167-5877

Publisher:

Elsevier

Language:

English

Submitter:

Susanne Agnes Lerch

Date Deposited:

22 May 2019 15:57

Last Modified:

22 May 2019 15:57

Publisher DOI:

10.1016/j.prevetmed.2018.02.009

PubMed ID:

29525235

Uncontrolled Keywords:

Bluetongue virus serotype 8 Cost-effectiveness analysis Cost-effectiveness optimisation Disease surveillance Risk-based surveillance Scenario tree modelling

BORIS DOI:

10.7892/boris.127854

URI:

https://boris.unibe.ch/id/eprint/127854

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