Application of a new laser Doppler imaging system in planning and monitoring of surgical flaps

Schlosser, Stefan; Wirth, Raphael; Plock, Jan A; Serov, Alexandre; Banic, Andrej; Erni, Dominique (2010). Application of a new laser Doppler imaging system in planning and monitoring of surgical flaps. Journal of biomedical optics, 15(3), p. 36023. Bellingham, Wash.: SPIE International Society for Optical Engineering 10.1117/1.3449598

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There is a demand for technologies able to assess the perfusion of surgical flaps quantitatively and reliably to avoid ischemic complications. The aim of this study is to test a new high-speed high-definition laser Doppler imaging (LDI) system (FluxEXPLORER, Microvascular Imaging, Lausanne, Switzerland) in terms of preoperative mapping of the vascular supply (perforator vessels) and postoperative flow monitoring. The FluxEXPLORER performs perfusion mapping of an area 9 x 9 cm with a resolution of 256 x 256 pixels within 6 s in high-definition imaging mode. The sensitivity and predictability to localize perforators is expressed by the coincidence of preoperatively assessed LDI high flow spots with intraoperatively verified perforators in nine patients. 18 free flaps are monitored before, during, and after total ischemia. 63% of all verified perforators correspond to a high flow spot, and 38% of all high flow spots correspond to a verified perforator (positive predictive value). All perfused flaps reveal a value of above 221 perfusion units (PUs), and all values obtained in the ischemic flaps are beneath 187 PU. In summary, we conclude that the present LDI system can serve as a reliable, fast, and easy-to-handle tool to detect ischemia in free flaps, whereas perforator vessels cannot be detected appropriately.

Item Type:	Journal Article (Original Article)
Division/Institute:	04 Faculty of Medicine > Department of Orthopaedic, Plastic and Hand Surgery (DOPH) > Clinic of Plastic and Hand Surgery > Hand Surgery 04 Faculty of Medicine > Department of Orthopaedic, Plastic and Hand Surgery (DOPH) > Clinic of Plastic and Hand Surgery > Plastic, Reconstructive and Aesthetic Surgery 08 Faculty of Science > Department of Chemistry, Biochemistry and Pharmaceutical Sciences (DCBP)
UniBE Contributor:	Schlosser, Stefan, Wirth, Raphael, Plock, Jan Alexander, Serov, Alexey, Banic, Andrej, Erni, Dominique
ISSN:	1083-3668
Publisher:	SPIE International Society for Optical Engineering
Language:	English
Submitter:	Factscience Import
Date Deposited:	04 Oct 2013 14:10
Last Modified:	05 Dec 2022 14:01
Publisher DOI:	10.1117/1.3449598
PubMed ID:	20615025
Web of Science ID:	000280642900038
URI:	https://boris.unibe.ch/id/eprint/1284 (FactScience: 202638)