Early complications after living donor nephrectomy: analysis of the Swiss Organ Living Donor Health Registry.

Burkhalter, Felix; Huynh-Do, Uyen; Hadaya, Karine; Matter, Maurice; Müller, Thomas; Binet, Isabelle; Nolte, Christa; Steiger, Juerg (2017). Early complications after living donor nephrectomy: analysis of the Swiss Organ Living Donor Health Registry. Swiss medical weekly, 147(w14497), w14497. EMH Media 10.4414/smw.2017.14497

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BACKGROUND We evaluated the prospectively collected data about the incidence of early peri- and postoperative complications, and potential risk factors for adverse outcomes after living kidney donation in Switzerland. METHODS Peri- and postoperative events were prospectively recorded on a questionnaire by the local transplant teams of all Swiss transplant centres and evaluated by the Swiss Organ Living Donor Health Registry. Complications were classified according to the Clavien grading system. A total of 1649 consecutive donors between 1998 and 2015 were included in the analysis. RESULTS There was no perioperative mortality observed. The overall complication rate was 13.5%. Major complications defined as Clavien ≥3 occurred in 2.1% of donors. Obesity was not associated with any complications. Donor age >70years was associated with major complications (odds ratio [OR] 3.99) and genitourinary complications (urinary tract infection OR 5.85; urinary retention OR 6.61). There were more major complications observed in donors with laparoscopic surgery versus open surgery (p = 0.048), but an equal overall complication rate (p = 0.094). CONCLUSION We found a low rate of major and minor complications, independent of surgical technique, after living donor nephrectomy. There was no elevated complication rate in obese donors. In contrast, elderly donors >70 years had an elevated risk for perioperative complications.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Nephrology and Hypertension

UniBE Contributor:

Huynh-Do, Uyen

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1424-3997

Publisher:

EMH Media

Language:

English

Submitter:

Uyen Huynh-Do

Date Deposited:

01 Oct 2019 13:04

Last Modified:

27 Oct 2019 07:54

Publisher DOI:

10.4414/smw.2017.14497

PubMed ID:

28871572

BORIS DOI:

10.7892/boris.131757

URI:

https://boris.unibe.ch/id/eprint/131757

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