Robust Cochlear Modiolar Axis Detection in CT

Wimmer, Wilhelm; Vandersteen, Clair; Guevara, Nicolas; Caversaccio, Marco; Delingette, Hervé (2019). Robust Cochlear Modiolar Axis Detection in CT (arXiv). Cornell University

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The cochlea, the auditory part of the inner ear, is a spiral-shaped organ with large morphological variability. An individualized assessment of its shape is essential for clinical applications related to tonotopy and cochlear implantation. To unambiguously reference morphological parameters, reliable recognition of the cochlear modiolar axis in computed tomography (CT) images is required. The conventional method introduces measurement uncertainties, as it is based on manually selected and difficult to identify landmarks. Herein, we present an algorithm for robust modiolar axis detection in clinical CT images. We define the modiolar axis as the rotation component of the kinematic spiral motion inherent in the cochlear shape. For surface fitting, we use a compact shape representation in a 7-dimensional kinematic parameter space based on extended Plücker coordinates. It is the first time such a kinematic representation is used for shape analysis in medical images. Robust surface fitting is achieved with an adapted approximate maximum likelihood method assuming a Student-t distribution, enabling axis detection even in partially available surface data. We verify the algorithm performance on a synthetic data set with cochlear surface subsets. In addition, we perform an experimental study with four experts in 23 human cochlea CT data sets to compare the automated detection with the manually found axes. Axes found from co-registered high resolution micro-CT scans are used for reference. Our experiments show that the algorithm reduces the alignment error providing more reliable modiolar axis detection for clinical and research applications.

Item Type:

Working Paper

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ear, Nose and Throat Disorders (ENT)
10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research > ARTORG Center - Image Guided Therapy > ARTORG Center - Artificial Hearing Research

UniBE Contributor:

Wimmer, Wilhelm and Caversaccio, Marco

Subjects:

600 Technology > 610 Medicine & health
600 Technology > 620 Engineering

Series:

arXiv

Publisher:

Cornell University

Funders:

[42] Schweizerischer Nationalfonds

Language:

English

Submitter:

Wilhelm Wimmer

Date Deposited:

02 Sep 2019 07:29

Last Modified:

14 Nov 2019 08:34

ArXiv ID:

1907.01870

BORIS DOI:

10.7892/boris.131888

URI:

https://boris.unibe.ch/id/eprint/131888

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