Associations of psychosis-risk symptoms with quality of life and self-rated health in the community

Michel, Chantal; Schmidt, Stefanie J.; Schnyder, Nina; Flückiger, Rahel; Käufeler, Iljana; Schimmelmann, Benno G.; Schultze-Lutter, Frauke (1 July 2019). Associations of psychosis-risk symptoms with quality of life and self-rated health in the community (Unpublished). In: 18th International Congress of the European Society for Child and Adolescent Psychiatry. Vienna, Austria. 30.06.-02.07.2019.

Objective: Understanding factors related to poor quality of life (QoL) and self-rated health (SRH) in clinical high risk (CHR) for psychosis is important for both research and clinical applications. We investigated the associations between both constructs with CHR symptoms, axis-I disorders, and sociodemographic variables in a general population sample. Methods: In total, 2,683 (baseline) and 829 (3-year follow-up) individuals of the Swiss Canton of Bern (age at baseline: 16–40 years) were interviewed by telephone regarding CHR symptoms, using the Schizophrenia Proneness Instrument for basic symptoms; ultra-high risk (UHR) symptoms using the Structured Interview for Prodromal Syndromes; current axis-I disorders, using the Mini-International Neuropsychiatric Interview; QoL, using the Brief Multidimensional Life Satisfaction Scale; and SRH using the 3-level EQ-5D. Results / Discussion: In cross-sectional structural equation modelling, lower SRH was significantly associated with higher age, male gender, lower education, and affective, anxiety, and somatoform disorders as well as UHR and basic symptoms, while poorer QoL was associated with affective, anxiety, and eating disorders, UHR, and basic symptoms. Prospectively, lower SRH was predicted by lower education and anxiety disorders at baseline, while poorer QoL was predicted by affective disorders at baseline. Conclusion: When present, CHR symptoms are already distressful for individuals in the community as they are associated with poorer subjective QoL and health. Therefore, the symptoms are clinically relevant by themselves, even when criteria for a CHR state are not fulfilled. Yet, unlike affective and anxiety disorders, CHR symptoms seem to have no long-term influence on QoL and SRH.

Item Type:

Conference or Workshop Item (Speech)

Division/Institute:

04 Faculty of Medicine > University Psychiatric Services > University Hospital of Child and Adolescent Psychiatry and Psychotherapy
07 Faculty of Human Sciences > Institute of Psychology > Clinical Psychology and Psychotherapy
04 Faculty of Medicine > University Psychiatric Services > University Hospital of Child and Adolescent Psychiatry and Psychotherapy > Research Division

UniBE Contributor:

Michel, Chantal; Schmidt, Stefanie Julia; Schnyder, Nina; Flückiger, Rahel and Schimmelmann, Benno Karl Edgar

Subjects:

600 Technology > 610 Medicine & health

Language:

English

Submitter:

Chantal Michel

Date Deposited:

27 Aug 2019 15:32

Last Modified:

27 Aug 2019 15:32

URI:

https://boris.unibe.ch/id/eprint/132469

Actions (login required)

Edit item Edit item
Provide Feedback