Symposium report: One Health meets sequencing.

Egli, Adrian; Koch, Daniel; Danuser, Jürg; Hendriksen, Rene S; Driesen, Susanne; Schmid, Diana Coman; Neher, Richard; Mäusezahl, Mirjam; Seth-Smith, Helena Mb; Bloemberg, Guido; Tschudin-Sutter, Sarah; Endimiani, Andrea; Perreten, Vincent; Greub, Gilbert; Schrenzel, Jacques; Stephan, Roger (2019). Symposium report: One Health meets sequencing. (In Press). Microbes and infection Elsevier Masson SAS 10.1016/j.micinf.2019.07.004

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Whole genome sequencing (WGS) has become the new gold standard for typing and characterization of pathogens. WGS enables understanding transmission chains of bacteria, exchange of mobile genetic elements, and variation in viruses with the highest resolution. In the near future, national and international databases will allow the tracking of pathogen transmissions based on WGS data in and across complex settings such as humans, animals, food, water and other environmental sources. Understanding the complexity and dynamics of and across these compartments will also help us to reduce transmissions of multi-drug resistant pathogens. Several important challenges for Public Health and One Health-related questions need to be identified such as defining standards for data analysis, accessing important epidemiological metadata, sharing data sharing while respecting data protection and ethical considerations. This symposium brought together leading institutions and fostered the ongoing discussion on the identified challenges, paving the way for solutions in public health, diagnostics, and research. This symposium report summarizes the key messages.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases > Research
04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Veterinary Bacteriology

UniBE Contributor:

Endimiani, Andrea and Perreten, Vincent

Subjects:

600 Technology > 630 Agriculture
500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health

ISSN:

1286-4579

Publisher:

Elsevier Masson SAS

Funders:

[4] Swiss National Science Foundation

Projects:

[1124] Whole Genome and Plasmid Sequencing for MDR Enterobacteriaceae Simultaneously Isolated from Multiple Human and Non-Human Settings: Deciphering Impact, Risks, and Dynamics for Resistance Transmission and Spread

Language:

English

Submitter:

Andrea Endimiani

Date Deposited:

28 Aug 2019 09:09

Last Modified:

22 Oct 2019 22:22

Publisher DOI:

10.1016/j.micinf.2019.07.004

PubMed ID:

31401354

Uncontrolled Keywords:

One Health Switzerland data protection ethics regulation whole genome sequencing

BORIS DOI:

10.7892/boris.132544

URI:

https://boris.unibe.ch/id/eprint/132544

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