Ways of calcium reabsorption in the kidney.

Moor, Matthias B.; Bonny, Olivier (2016). Ways of calcium reabsorption in the kidney. American journal of physiology. Renal physiology, 310(11), F1337-F1350. American Physiological Society 10.1152/ajprenal.00273.2015

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The role of the kidney in calcium homeostasis has been reshaped from a classic view in which the kidney was regulated by systemic calcitropic hormones such as vitamin D3 or parathyroid hormone to an organ actively taking part in the regulation of calcium handling. With the identification of the intrinsic renal calcium-sensing receptor feedback system, the regulation of paracellular calcium transport involving claudins, and new paracrine regulators such as klotho, the kidney has emerged as a crucial modulator not only of calciuria but also of calcium homeostasis. This review summarizes recent molecular and endocrine contributors to renal calcium handling and highlights the tight link between calcium and sodium reabsorption in the kidney.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Nephrology and Hypertension

UniBE Contributor:

Moor, Matthias

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1522-1466

Publisher:

American Physiological Society

Language:

English

Submitter:

Matthias Moor

Date Deposited:

08 Oct 2019 14:18

Last Modified:

05 Dec 2022 15:30

Publisher DOI:

10.1152/ajprenal.00273.2015

PubMed ID:

27009338

Uncontrolled Keywords:

calcium hypercalciuria kidney stones nephrocalcinosis osteoporosis sodium

URI:

https://boris.unibe.ch/id/eprint/133427

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