Scaffold and organism hopping with chemical probes.

Gertsch, Jürg (2019). Scaffold and organism hopping with chemical probes. Nature chemical biology, 15(5), pp. 428-429. Springer Nature 10.1038/s41589-019-0275-9

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Chemical probes that irreversibly inhibit protein function may be used across species to discover proteins. Combining phenotypic screening and activity-based protein profiling, a new study uncovers a discrete lipid signaling pathway regulating lifespan in the worm Caenorhabditis elegans.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Faculty Institutions > NCCR TransCure
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Biochemistry and Molecular Medicine

UniBE Contributor:

Gertsch, Jürg

Subjects:

500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health

ISSN:

1552-4469

Publisher:

Springer Nature

Language:

English

Submitter:

Barbara Järmann-Bangerter

Date Deposited:

26 Sep 2019 15:00

Last Modified:

05 Nov 2019 04:30

Publisher DOI:

10.1038/s41589-019-0275-9

PubMed ID:

30992560

BORIS DOI:

10.7892/boris.133492

URI:

https://boris.unibe.ch/id/eprint/133492

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