Gertsch, Jürg (2019). Scaffold and organism hopping with chemical probes. Nature chemical biology, 15(5), pp. 428-429. Springer Nature 10.1038/s41589-019-0275-9
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Chemical probes that irreversibly inhibit protein function may be used across species to discover proteins. Combining phenotypic screening and activity-based protein profiling, a new study uncovers a discrete lipid signaling pathway regulating lifespan in the worm Caenorhabditis elegans.
Item Type: |
Journal Article (Further Contribution) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Faculty Institutions > NCCR TransCure 04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Biochemistry and Molecular Medicine |
UniBE Contributor: |
Gertsch, Jürg |
Subjects: |
500 Science > 570 Life sciences; biology 600 Technology > 610 Medicine & health |
ISSN: |
1552-4469 |
Publisher: |
Springer Nature |
Language: |
English |
Submitter: |
Barbara Franziska Järmann-Bangerter |
Date Deposited: |
26 Sep 2019 15:00 |
Last Modified: |
05 Dec 2022 15:30 |
Publisher DOI: |
10.1038/s41589-019-0275-9 |
PubMed ID: |
30992560 |
BORIS DOI: |
10.7892/boris.133492 |
URI: |
https://boris.unibe.ch/id/eprint/133492 |
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