Percutaneous stereotactic image-guided microwave ablation for malignant liver lesions.

Perrodin, Stéphanie; Lachenmayer, Anja; Maurer, Martin; Kim-Fuchs, Corina; Candinas, Daniel; Banz, Vanessa (2019). Percutaneous stereotactic image-guided microwave ablation for malignant liver lesions. Scientific reports, 9(1), p. 13836. Springer Nature 10.1038/s41598-019-50159-3

[img]
Preview
Text
Percutaneous_Perrodin.pdf - Published Version
Available under License Creative Commons: Attribution (CC-BY).

Download (959kB) | Preview

Thermal ablation has proven beneficial for hepatocellular carcinoma and possibly for colorectal liver metastases, but data is lacking for other liver metastases. Computer-assisted navigation can increase ablation efficacy and broaden its indications. We present our experience with percutaneous stereotactic image-guided microwave ablation (SMWA) for non-colorectal liver metastases (NCRLM), in form of a retrospective study including all SMWA for NCRLM from 2015 to 2017. Indication for SMWA was determined at a multidisciplinary tumorboard. End-points include recurrence, overall and liver-specific disease progression and complications. Twenty-three patients underwent 25 interventions for 40 lesions, including 17 neuroendocrine tumor, nine breast cancer, four sarcoma, two non-small cell lung cancer, three duodenal adenocarcinoma, one esophageal adenocarcinoma, one pancreatic adenocarcinoma, one ampullary carcinoma, one prostate carcinoma, and one renal cell carcinoma metastases. Median follow-up was 15 months (2-32). Incomplete ablation rate was 2.5% (1/40), local recurrence rate 10% (4/40). Three patients (12%) had minor complications. Overall disease progression was 73.9% (17/23), median disease-free survival 7 months (0-26) and overall survival 18 months (2-39). SIMWA is feasible, safe and minimally invasive for NCRLM in selected patients. While it might offer an alternative to resection or palliative strategies, the oncological benefit needs to be evaluated in a larger patient cohort.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Visceral Surgery
04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology

UniBE Contributor:

Perrodin, Stéphanie Fabienne; Lachenmayer, Anja; Maurer, Martin; Kim-Fuchs, Corina; Candinas, Daniel and Banz Wüthrich, Vanessa

Subjects:

600 Technology > 610 Medicine & health

ISSN:

2045-2322

Publisher:

Springer Nature

Language:

English

Submitter:

Maria de Fatima Henriques Bernardo

Date Deposited:

01 Oct 2019 15:24

Last Modified:

23 Oct 2019 13:14

Publisher DOI:

10.1038/s41598-019-50159-3

PubMed ID:

31554853

BORIS DOI:

10.7892/boris.133607

URI:

https://boris.unibe.ch/id/eprint/133607

Actions (login required)

Edit item Edit item
Provide Feedback