Health related quality of life and manual ability 5 years after neonatal ischemic stroke.

Caspar-Teuscher, Miriam; Studer, Martina; Regényi, Mária; Steinlin, Maja; Grunt, Sebastian (2019). Health related quality of life and manual ability 5 years after neonatal ischemic stroke. European journal of paediatric neurology, 23(5), pp. 716-722. Elsevier 10.1016/j.ejpn.2019.08.002

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AIM To investigate health-related quality of life (HRQOL) and manual ability five years after neonatal arterial ischemic stroke (NAIS). METHODS Data was prospectively obtained by the Swiss Neuropaediatric Stroke Registry between 2000 and 2010. Two years after NAIS, cognitive and motor outcomes was assessed using the Bayley Scales of Infant Development (BSID-II). After 5 years, HRQOL was assessed with the KIDSCREEN-27 and manual ability with the ABILHAND-Kids. Manual ability and HRQOL were compared between children with and without cerebral palsy (CP) and HRQOL was correlated with manual ability. RESULTS Seventy-four patients were examined at the age of 2 years, at the age of 5 years 61 patients underwent a follow-up examination. Two years after NAIS, 29 children (39.1%) were diagnosed with CP. HRQOL 5 years after NAIS was comparable to normative values. Children with CP had a significantly lower HRQOL-index (p = 0.013) and lower scores in the subscale psychological well-being (p = 0.012) and social support & peers (p = 0.048). The ABILHAND-Kids measure was significantly lower in children with CP compared to children without CP (p < 0.001). Manual ability correlated significantly with HRQOL. CONCLUSION Five years after NAIS, HRQOL is comparable to that of typically developing peers, but reduced in children with CP. Poorer manual ability is associated with lower HRQOL. Interventions improving hand function might influence HRQOL and should be considered early on.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine

UniBE Contributor:

Studer, Martina; Regényi, Mária and Grunt, Sebastian

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1090-3798

Publisher:

Elsevier

Language:

English

Submitter:

Karen Lidzba

Date Deposited:

21 Oct 2019 13:22

Last Modified:

03 Nov 2019 01:32

Publisher DOI:

10.1016/j.ejpn.2019.08.002

PubMed ID:

31473077

Uncontrolled Keywords:

Cerebral palsy Hemiparesis Manual ability Neonatal arterial ischemic stroke Quality of life

BORIS DOI:

10.7892/boris.134045

URI:

https://boris.unibe.ch/id/eprint/134045

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