Shaul, Chanan; Bester, Christofer W; Weder, Stefan; Choi, June; Eastwood, Hayden; Padmavathi, K V; Collins, Aaron; O'Leary, Stephen J (2019). Electrical Impedance as a Biomarker for Inner Ear Pathology Following Lateral Wall and Peri-modiolar Cochlear Implantation. Otology & neurotology, 40(5), e518-e526. Wolters Kluwer 10.1097/MAO.0000000000002227
Full text not available from this repository. (Request a copy)OBJECTIVES/HYPOTHESIS
Spikes in cochlear implant impedance are associated with inner ear pathology after implantation. Here, we correlate these spikes with episodes of hearing loss and/or vertigo, with a comparison between lateral wall and peri-modiolar electrode arrays.
METHODS
Seven hundred seventy recipients of Cochlear's slim-straight, lateral wall electrode (CI422), or peri-modiolar (CI512) electrode were investigated for impedance spikes. Impedance fluctuations were defined as a median rise of ≥ 4 kΩ across all intracochlear electrodes from baseline measurements taken 2 weeks after switch-on. Medical records were analyzed from 189 of the 770 patients.
RESULTS
The slim straight, lateral wall electrode was found to spike in impedance at a significantly higher rate than the peri-modiolar array (17% vs 12%). The peri-modiolar electrode tended to spike in impedance earlier than the slim-straight electrode. Impedance spikes were found to significantly correlate with medical events (hearing loss, vertigo, or tinnitus). Overall, in the "spike" group, 42 of 75 patients (56%) demonstrated a clinical event during the impedance spike, whereas 26 of 114 patients (22%) of the "non-spike" group had a clinical event. This significant difference existed with both implant types.
CONCLUSION
These results demonstrate a small, but significant increase in impedance spikes in lateral wall electrodes, and support the relationship between spikes in cochlear implant impedances and postoperative inner-ear events, including the loss of residual hearing and vertigo. Monitoring cochlear implant impedance may be a method for early detection, and so the prevention, of these events in the future.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ear, Nose and Throat Disorders (ENT) |
UniBE Contributor: |
Weder, Stefan Andreas |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1537-4505 |
Publisher: |
Wolters Kluwer |
Language: |
English |
Submitter: |
Stefan Weder |
Date Deposited: |
14 Jan 2020 15:30 |
Last Modified: |
02 Mar 2023 23:32 |
Publisher DOI: |
10.1097/MAO.0000000000002227 |
PubMed ID: |
31083087 |
URI: |
https://boris.unibe.ch/id/eprint/134069 |
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