A review on potential toxicity of dental material and screening their biocompatibility.

Shahi, Shahriar; Özcan, Mutlu; Maleki Dizaj, Solmaz; Sharifi, Simin; Al-Haj Husain, Nadin; Eftekhari, Aziz; Ahmadian, Elham (2019). A review on potential toxicity of dental material and screening their biocompatibility. Toxicology mechanisms and methods, 29(5), pp. 368-377. Taylor & Francis 10.1080/15376516.2019.1566424

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OBJECTIVES

A wide range of compounds are utilized in dentistry such as dental composites, resins, and implants. The successful clinical use of dental materials relies on theirm physiochemical properties as well as biological and toxicological reliability. Different local and systemic toxicities of dental materials have been reported. Placement of these materials in oral cavity for a long time period might yield unwanted reactions. An extensive variety of materials is used in dentistry including filling materials, restorative materials, intracanal medicines, prosthetic materials, different types of implants, liners, and irrigants. The increasing rate in development of the novel materials with applications in the dental field has led to an increased consciousness of the biological risks and tempting restrictions of these materials. The biocompatibility of a biomaterial used for the replacement or filling of biological tissue such as teeth always had a high concern within the health care disciplines for patients.

MATERIALS AND METHODS

Any material used in humans should be tested before clinical application. There are many tests evaluating biocompatibility of these materials at the point of in vitro, in vivo, and clinical investigations.

RESULTS

The current review discusses the potential toxicity of dental material and screening of their biocompatibility.

CLINICAL RELEVANCE

It is essential to use healthy and safe materials medical approaches. In dentistry, application of different materials in long-term oral usage demands low or nontoxic agents gains importance for both patients and the staff. Furthermore, screening tests should evaluate any potential toxicity before clinical application.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > School of Dental Medicine > Department of Reconstructive Dentistry and Gerodontology

UniBE Contributor:

Al-Haj Husain, Nadin

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1537-6524

Publisher:

Taylor & Francis

Language:

English

Submitter:

Vanda Kummer

Date Deposited:

11 Nov 2019 13:43

Last Modified:

05 Feb 2020 02:30

Publisher DOI:

10.1080/15376516.2019.1566424

PubMed ID:

30642212

Uncontrolled Keywords:

Biocompatibility dental materials dentistry oral health toxicity toxicology

BORIS DOI:

10.7892/boris.134343

URI:

https://boris.unibe.ch/id/eprint/134343

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