[From Axial Spondyloarthritis to Osteoporosis - Spectrum of Skeletal Involvement in Inflammatory Bowel Diseases].

Schüle, Solvey; Frey, Diana; Biedermann, Luc; Grueber, Maude Martinho; Zeitz, Jonas; Vavricka, Stephan; Möller, Burkhard; Rogler, Gerhard; Misselwitz, Benjamin (2019). [From Axial Spondyloarthritis to Osteoporosis - Spectrum of Skeletal Involvement in Inflammatory Bowel Diseases]. Praxis, 108(12), pp. 799-806. Hogrefe 10.1024/1661-8157/a003301

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From Axial Spondyloarthritis to Osteoporosis - Spectrum of Skeletal Involvement in Inflammatory Bowel Diseases Abstract. Inflammatory bowel diseases (IBD) are frequently accompanied by non-inflammatory joint pain and inflammatory spondyloarthritides. Spondyloarthritides can restrict joint function and typically manifest with inflammatory back pain with nightly pain and morning stiffness that improves upon exercising. In other patients, small or large peripheral joints are predominantly involved. Treatment comprises pain medication including COX-II selective non-steroidal anti-inflammatory drugs (NSAID), since non-selective NSAID can aggravate IBD. For axial manifestations, physiotherapy and tumor necrosis factor (TNF) inhibitors are effective, while for peripheral manifestations steroid injections, sulfasalazine and TNF inhibitors are useful. Osteopenia and osteoporosis may result from inflammation, malabsorption and/or steroids. Long-lasting disease activity or steroid treatment should prompt osteoporosis screening. Adequate calcium and vitamin D intake must be ensured and treatment with bisphosphonates evaluated.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Rheumatology, Clinical Immunology and Allergology
04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine

UniBE Contributor:

Martinho-Grüber, Maude Delphine, Möller, Burkhard

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1661-8157

Publisher:

Hogrefe

Language:

German

Submitter:

Burkhard Möller

Date Deposited:

08 Nov 2019 09:39

Last Modified:

02 Mar 2023 23:32

Publisher DOI:

10.1024/1661-8157/a003301

PubMed ID:

31530124

Uncontrolled Keywords:

Arthralgie Chronisch entzündliche Darmerkrankungen Inflammatory bowel disease Maladie inflammatoire chronique de l’intestin Osteopenie Osteoporose arthralgia arthropathie axial spondyloarthritis axiale Spondyloarthritis extraintestinal manifestations extraintestinale Manifestationen manifestations extra-intestinales osteopenia osteoporosis ostéoporose ostéopénie

BORIS DOI:

10.7892/boris.134785

URI:

https://boris.unibe.ch/id/eprint/134785

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