Hertig-Godeschalk, Anneke; Skorucak, Jelena; Malafeev, Alexander; Achermann, Peter; Mathis, Johannes; Schreier, David R. (2020). Microsleep episodes in the borderland between wakefulness and sleep. Sleep, 43(1) Oxford University Press 10.1093/sleep/zsz163
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Hertig_Godeschalk, 2019, Microsleep episodes in the borderland between wakefulness and sleep.pdf - Accepted Version Available under License Publisher holds Copyright. Download (1MB) | Preview |
STUDY OBJECTIVES
The wake-sleep transition zone represents a poorly defined borderland, containing e.g. microsleep episodes (MSEs) which are of potential relevance for diagnosis and may have consequences while driving. Yet, the scoring guidelines of the American Academy of Sleep Medicine (AASM) completely neglect it. We aimed to explore the borderland between wakefulness and sleep by developing the Bern continuous and high-resolution wake-sleep (BERN) criteria for visual scoring, focusing on MSEs visible in the electroencephalogram (EEG), as opposed to purely behaviour- or performance-defined MSEs.
METHODS
Maintenance of Wakefulness Test (MWT) trials of 76 randomly selected patients were retrospectively scored according to both the AASM and the newly developed BERN scoring criteria. The visual scoring was compared with spectral analysis of the EEG. The quantitative EEG analysis enabled a reliable objectification of the visually scored MSEs. For less distinct episodes within the borderland, either ambiguous or no quantitative patterns were found.
RESULTS
As expected, the latency to the first MSE was significantly shorter in comparison to the sleep latency, defined according to the AASM criteria. In certain cases, a large difference between the two latencies was observed, and a substantial number of MSEs occurred between the first MSE and sleep. Series of MSEs were more frequent in patients with shorter sleep latencies, while isolated MSEs were more frequent in patients who did not reach sleep.
CONCLUSION
The BERN criteria extend the AASM criteria and represent a valuable tool for in-depth analysis of the wake-sleep transition zone, particularly important in the MWT.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology |
UniBE Contributor: |
Godeschalk, Anneke Grietje Elizabeth, Mathis, Johannes, Schreier, David Raphael |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1550-9109 |
Publisher: |
Oxford University Press |
Language: |
English |
Submitter: |
Chantal Kottler |
Date Deposited: |
11 Nov 2019 15:29 |
Last Modified: |
05 Dec 2022 15:32 |
Publisher DOI: |
10.1093/sleep/zsz163 |
PubMed ID: |
31328230 |
Uncontrolled Keywords: |
AASM scoring criteria Microsleep electroencephalography maintenance of wakefulness test sleep sleepiness wake-sleep transition zone wakefulness |
BORIS DOI: |
10.7892/boris.134858 |
URI: |
https://boris.unibe.ch/id/eprint/134858 |
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