Virus-like particles for vaccination against cancer.

Mohsen, Mona O.; Speiser, Daniel E; Knuth, Alexander; Bachmann, Martin F. (2020). Virus-like particles for vaccination against cancer. Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology, 12(1), e1579. Wiley 10.1002/wnan.1579

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Active immunotherapy of cancer aims to treat the disease by inducing effective cellular and humoral immune responses. Virus-like particle-based vaccines have evolved dramatically over the last few decades, greatly reducing morbidity and mortality of several infectious diseases and expectedly preventing cervical cancer caused by human papilloma virus. In contrast to these broad successes of disease prevention, therapeutic cancer vaccines remain to demonstrate clinical benefit. Yet, several preclinical and clinical trials have revealed promising results and are paving the way for medical breakthroughs. This study reviews and discusses the recent preclinical development and clinical trials in this field. This article is categorized under: Biology-Inspired Nanomaterials > Protein and Virus-Based Structures Nanotechnology Approaches to Biology > Nanoscale Systems in Biology.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Rheumatologie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Rheumatologie

UniBE Contributor:

Mohsen, Mona Omar Mahmoud and Bachmann, Martin

ISSN:

1939-0041

Publisher:

Wiley

Language:

English

Submitter:

Lee-Anne Brand

Date Deposited:

15 Nov 2019 16:05

Last Modified:

14 Dec 2019 01:32

Publisher DOI:

10.1002/wnan.1579

PubMed ID:

31456339

Uncontrolled Keywords:

cancer vaccine virus like particles

BORIS DOI:

10.7892/boris.135086

URI:

https://boris.unibe.ch/id/eprint/135086

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