Das Kreuz mit der Kreuzallergie: Betalaktamantibiotika-Allergie

Jörg, Lukas; Helbling, Arthur (2019). Das Kreuz mit der Kreuzallergie: Betalaktamantibiotika-Allergie. Therapeutische Umschau, 76(1), pp. 7-11. Hogrefe 10.1024/0040-5930/a001055

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Hypersensitivity reactions to betalactam antibiotics are the most commonly mentioned drug allergies. Up to 10 percent of patients report to suffer from a penicillin allergy. However, classical side effects of antibiotics are often misdiagnosed as an allergy. Many of these patients with suspected betalactam allergy tolerate betalactam antibiotics well. Therefore, a thorough allergy workup is essential to confirm a suspected allergy or to enable again a treatment with betalactam antibiotics. Most important is a good documentation as skin- and in-vitro tests have a reduced sensitivity. Gold standard is the provocation test to help exclude a supposed allergy or to test alternative, potential cross reactive betalactam antibiotics. Cross-reactions between penicillins and cephalosporins, especially cephalosporins of the third and fourth generation are unusual. Cross reactions to carbapenem antibiotics are rare.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Rheumatology, Clinical Immunology and Allergology

UniBE Contributor:

Jörg, Lukas, Helbling, Arthur

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0040-5930

Publisher:

Hogrefe

Language:

German

Submitter:

Lukas Jörg

Date Deposited:

21 Nov 2019 13:46

Last Modified:

05 Dec 2022 15:32

Publisher DOI:

10.1024/0040-5930/a001055

PubMed ID:

31282836

URI:

https://boris.unibe.ch/id/eprint/135174

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