Nardi, Gianna Maria; Grassi, Roberta; Campus, Guglielmo; Pareti, Maria Letizia; Di Stasio, Dario; Della Vella, Fedora (2019). A chlorhexidine-containing brush-on gel as adjuvant treatment for plaque induced gingivitis. (In Press). Current topics in medicinal chemistry Bentham Science Publishers 10.2174/1568026619666191114120218
Full text not available from this repository. (Request a copy)AIM:
The aim of the present study was to evaluate the effects of a chlorhexidine brush-on gel application on plaque-induced gingivitis.
MATERIALS & METHODS:
Consecutive patients diagnosed with gingivitis were enrolled. For each patient, full mouth plaque score and gingival index were recorded during the first visit (t0) and after 1 week (t1), 2 weeks (t2) and 3 weeks (t3). Patients were randomly divided into a study group, who received instruction to brush their teeth daily with a chlorhexidine-based gel, and a control group, treated with a placebo gel. The chi-square test was used to compare the groups baseline, while the t-Student and the Mann-Whitney tests were performed to evaluate the significance of groups indexes improvement, individually and compared.
RESULTS:
Thirty participants were enrolled: 15 referred to the study group and 15 to the control group. The study group showed a reduction of plaque score and gingival index of 87% and 84% respectively (p<0.05), while the control group plaque score and gingival index decreased of 75% and 80% (p<0.05). The study group plaque score reduction resulted to be statistically more significant than the control group one.
CONCLUSIONS:
The topical application of a chlorhexidine-based brush-on gel can be a useful adjunctive domiciliary treatment for gingivitis therapy, combined with the mechanical debridement, that still remains the gold standard.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > School of Dental Medicine > Department of Preventive, Restorative and Pediatric Dentistry |
UniBE Contributor: |
Campus, Guglielmo Giuseppe |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1568-0266 |
Publisher: |
Bentham Science Publishers |
Language: |
English |
Submitter: |
Guglielmo Giuseppe Campus |
Date Deposited: |
04 Dec 2019 09:01 |
Last Modified: |
05 Dec 2022 15:32 |
Publisher DOI: |
10.2174/1568026619666191114120218 |
PubMed ID: |
31724501 |
Uncontrolled Keywords: |
Chlorhexidine; Gingivitis; Oral Hygiene; Topical Gel |
URI: |
https://boris.unibe.ch/id/eprint/135214 |
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