How old is old for implant therapy in terms of early implant losses?

Bertl, Kristina; Ebner, Maria; Knibbe, Marianne; Pandis, Nikolaos; Kuchler, Ulrike; Ulm, Christian; Stavropoulos, Andreas (2019). How old is old for implant therapy in terms of early implant losses? Journal of clinical periodontology, 46(12), pp. 1282-1293. Wiley 10.1111/jcpe.13199

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OBJECTIVES To assess, retrospectively, whether older age has an impact on implant osseointegration when compared with younger age. METHODS All patients ≥65 years old at implant installation, in an university setting over a time-period of 11.5 years, with complete anamnestic data and follow-up until prosthetic restoration were included, and any early implant loss (EIL; i.e. lack of osseointegration prior to or at the time-point of prosthetic restoration) was recorded. Further, one implant, from each of the elderly patients, was attempted matched to one implant in a younger patient (35 to <55 years old at implant installation) from the same clinic based on (a) gender, (b) implant region, (c) smoking status and (d) bone grafting prior to/simultaneously with implant installation. The potential impact of various local and systemic factors on EIL in the entire elderly population, and in the matched elderly and younger patient group was statistically assessed. RESULTS Four hundred forty-four patients ≥65 years old (range 65.1-91.3; 56.8% female) receiving 1,517 implants were identified; 10 patients had one EIL each (implant/patient level: 0.66/2.25%). Splitting this patient cohort additionally into four age groups [65-69.9 (n = 213), 70-74.9 (n = 111), 75-79.9 (n = 80) and ≥80 (n = 40)], EIL was on the implant level 0.41, 0.83, 0.34 and 2.26%, respectively, (p = .102) and on the patient level 1.41, 2.70, 1.25 and 7.50%, respectively, (p = .104); multilevel analysis showed weak evidence of association of increasing age with higher EIL rate (p = .090). Matching was possible in 347 cases, and 5 (1.44%) and 9 (2.59%) EIL in the elderly and younger patients, respectively, were observed (p = .280). EIL could not be associated with any systemic condition or medication intake. CONCLUSIONS Elderly patients ≥65 years old presented a similarly low EIL rate as younger patients 35 to <55 years old, while patients ≥80 years old may have a slight tendency for a higher EIL rate. Hence, ageing does not seem to compromise osseointegration, and if at all, then only slightly and at a later stage of life.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > School of Dental Medicine > Department of Orthodontics

UniBE Contributor:

Pandis, Nikolaos


600 Technology > 610 Medicine & health








Renate Imhof-Etter

Date Deposited:

22 Nov 2019 15:52

Last Modified:

22 Nov 2019 15:52

Publisher DOI:


PubMed ID:


Uncontrolled Keywords:

dental implant early implant loss elderly population osseointegration




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