Rios-Leyvraz, Magali; Bochud, Murielle; Benzi Schmid, Clara; Haldimann, Max; Bovet, Pascal; Chiolero, Arnaud (2020). Population biomonitoring of micronutrient intakes in children using urinary spot samples. European Journal of Nutrition, 59(7), pp. 3059-3068. Springer-Verlag 10.1007/s00394-019-02144-9
|
Text
Rios-Leyvraz EurJNutr 2020_p3059.pdf - Published Version Available under License Publisher holds Copyright. Download (2MB) | Preview |
|
|
Text
Rios-Leyvraz EurJNutr 2019_postprint.pdf - Accepted Version Available under License Publisher holds Copyright. Download (118kB) | Preview |
PURPOSE
Urinary spot samples are a promising method for the biomonitoring of micronutrient intake in children. Our aim was to assess whether urinary spot samples could be used to estimate the 24-h urinary excretion of potassium, phosphate, and iodine at the population level.
METHODS
A cross-sectional study of 101 children between 6 and 16 years of age was conducted. Each child collected a 24-h urine collection and three urinary spot samples (evening, overnight, and morning). Several equations were used to estimate 24-h excretion based on the urinary concentrations of each micronutrient in the three spot samples. Various equations and spot combinations were compared using several statistics and plots.
RESULTS
Ninety-four children were included in the analysis (mean age: 10.5 years). The mean measured 24-h urinary excretions of potassium, phosphate, and iodine were 1.76 g, 0.61 g, and 95 µg, respectively. For potassium, the best 24-h estimates were obtained with the Mage equation and morning spot (mean bias: 0.2 g, correlation: 0.27, precision: 56%, and misclassification: 10%). For phosphate, the best 24-h estimates were obtained with the Mage equation and overnight spot (mean bias: - 0.03 g, correlation: 0.54, precision: 72%, and misclassification: 10%). For iodine, the best 24-h estimates were obtained with the Remer equation and overnight spot (mean bias: - 8 µg, correlation: 0.58, precision: 86%, misclassification: 16%).
CONCLUSIONS
Urinary spot samples could be a good alternative to 24-h urine collection for the population biomonitoring of iodine and phosphate intakes in children. For potassium, spot samples were less reliable.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Medical Education > Institute of General Practice and Primary Care (BIHAM) |
UniBE Contributor: |
Chiolero, Arnaud |
Subjects: |
600 Technology > 610 Medicine & health 300 Social sciences, sociology & anthropology > 360 Social problems & social services |
ISSN: |
1436-6207 |
Publisher: |
Springer-Verlag |
Language: |
English |
Submitter: |
Doris Kopp Heim |
Date Deposited: |
26 Nov 2019 09:30 |
Last Modified: |
21 Nov 2023 00:25 |
Publisher DOI: |
10.1007/s00394-019-02144-9 |
PubMed ID: |
31745727 |
Uncontrolled Keywords: |
Children Iodine Phosphate Potassium Urinary excretion Urinary spots |
BORIS DOI: |
10.7892/boris.135691 |
URI: |
https://boris.unibe.ch/id/eprint/135691 |
Actions (login required)
 |
Edit item |