Capillary electrophoresis for the determination of drugs in biological fluids

Thormann, Wolfgang (2020). Capillary electrophoresis for the determination of drugs in biological fluids. In: Hempel, Georg (ed.) Methods of Therapeutic Drug Monitoring including Pharmacogenetics. Handbook of Analytical Separations: Vol. 7 (pp. 81-96). Amsterdam: Elsevier 10.1016/B978-0-444-64066-6.00004-6

Text Hempel book chapter on CE of drugs in biofluids.pdf - Published Version Restricted to registered users only Available under License Publisher holds Copyright. Download (579kB) | Request a copy

Capillary electrophoresis (CE) is an effective and economic tool for analysis of licit and illicit drugs and their metabolites in biological samples. This chapter provides a brief overview of the principles of CE, the features of CE instrumentation and the key aspects of CE-based drug assays that were developed for therapeutic drug monitoring, clinical and forensic toxicology and the assessment of drug metabolism and pharmacokinetics.

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