Variations in radioiodine ablation: decision-making after total thyroidectomy.

Maas, O; Forrer, F; Maas, M; Panje, C. M.; Blautzik, J; Brühlmeier, M; Engel-Bicik, I; Giovanella, L; Haldemann, A; Kamel, M E; Kneifel, S; Rottenburger, C; Schaefer, N; Walter, M A; Weidner, Sabine; Putora, Paul Martin (2020). Variations in radioiodine ablation: decision-making after total thyroidectomy. European journal of nuclear medicine and molecular imaging, 47(3), pp. 554-560. Springer-Verlag 10.1007/s00259-019-04557-4

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BACKGROUND The role of radioiodine treatment following total thyroidectomy for differentiated thyroid cancer is changing. The last major revision of the American Thyroid Association (ATA) Management Guidelines for Patients with Thyroid Nodules and Differentiated Thyroid Cancer in 2015 changed treatment recommendations dramatically in comparison with the European Association of Nuclear Medicine (EANM) 2008 guidelines. We hypothesised that there is marked variability between the different treatment regimens used today. METHODS We analysed decision-making in all Swiss hospitals offering radioiodine treatment to map current practice within the community and identify consensus and discrepancies. RESULTS AND CONCLUSION: We demonstrated that for low-risk DTC patients after thyroidectomy, some institutions offered only follow-up, while RIT with significant activities is recommended in others. For intermediate- and high-risk patients, radioiodine treatment is generally recommended. Dosing and treatment preparation (recombinant human thyroid stimulation hormone (rhTSH) vs. thyroid hormone withdrawal (THW)) vary significantly among centres.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Radiation Oncology
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Clinic of Nuclear Medicine

UniBE Contributor:

Weidner, Sabine Edith and Putora, Paul Martin

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1619-7070

Publisher:

Springer-Verlag

Language:

English

Submitter:

Beatrice Scheidegger

Date Deposited:

18 Dec 2019 08:34

Last Modified:

08 Feb 2020 01:32

Publisher DOI:

10.1007/s00259-019-04557-4

PubMed ID:

31707428

Uncontrolled Keywords:

Decision Making Radioiodine Thyroidectomy Treatment

BORIS DOI:

10.7892/boris.136371

URI:

https://boris.unibe.ch/id/eprint/136371

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