Alcohol-Specific Computerized Interventions to Alter Cognitive Biases: A Systematic Review of Effects on Experimental Tasks, Drinking Behavior, and Neuronal Activation

Batschelet, Hallie M.; Stein, Maria; Tschümperlin, Raphaela M.; Soravia, Leila M.; Moggi, Franz (2020). Alcohol-Specific Computerized Interventions to Alter Cognitive Biases: A Systematic Review of Effects on Experimental Tasks, Drinking Behavior, and Neuronal Activation. Frontiers in psychiatry, 10 Frontiers 10.3389/fpsyt.2019.00871

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Background: In patients with alcohol use disorder, novel interventions to increase
abstinence have attracted growing attention. Interventions aimed at modifying cognitive
biases linked to alcohol use [i.e. cognitive bias modification (CBM)] may serve as an
add-on to standard therapy. This systematic review thoroughly aggregates existing data
on the effects of three alcohol-specific computerized interventions, namely attentional
bias modification (AtBM), approach bias modification (ApBM), and inhibition training (IT).
In doing so, each CBM’s effects on experimental tasks assessing the relevant biases,
drinking behavior, and neurophysiology are summarized. Also, the influence of drinking
behavior severity and motivation to change drinking behavior are discussed.

Methods: A literature search was conducted in four databases for original research
articles published between 2000 and May 2019. Studies were eligible if investigating
the effects of alcohol-specific computerized interventions (AtBM, ApBM, IT) on drinking
behavior, bias change, and/or neurophysiology. Forty eligible articles were classified as
being either a non-clinical experimental lab study (ELS) or clinical randomized-controlled
trial (RCT) and summarized.

Results: While AtBM seems to influence attentional bias, its effects on drinking behavior
are inconsistent. As for ApBM, the best effects on drinking behavior are obtained in clinical
samples. Effects of ApBM on approach bias are mixed. Interestingly, those clinical RCTs
which investigated ApBM effects on bias change as well as on drinking outcome, reported
consistent effects in both measures (i.e. either effects on bias and drinking or no effects).
Studies on IT are limited to non-clinical samples and show inconsistent effects on drinking
behavior. Considering ITs effects on implicit semantic associations, most studies do not
support the conceptualization of IT as a form of memory bias modification, while reports on
IT’s effects on inhibitory control are still incomplete. Conclusions about the overall influence
of drinking behavior severity are hampered by the non-uniform use of sample descriptions.

Conclusions: In clinical samples, ApBM has shown more consistent beneficial effects,
while evidence on AtBM is more inconsistent, and data on IT still lacks important
information. Conclusions about the influence of drinking behavior severity would be
facilitated by a uniform use of clearly defined sample descriptions.

Item Type:

Journal Article (Review Article)


04 Faculty of Medicine > University Psychiatric Services > University Hospital of Psychiatry and Psychotherapy > Translational Research Center
07 Faculty of Human Sciences > Institute of Psychology > Clinical Psychology and Psychotherapy

Graduate School:

Graduate School for Health Sciences (GHS)

UniBE Contributor:

Batschelet, Hallie Margareta, Stein, Maria, Tschümperlin, Raphaela Martina, Soravia, Leila, Moggi, Franz (A)


600 Technology > 610 Medicine & health








Hallie Margareta Batschelet

Date Deposited:

13 Jan 2020 11:28

Last Modified:

29 Mar 2023 23:36

Publisher DOI:





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