Damiani, Giovanni; Cazzaniga, Simone; Conic, Rosalynn Rz; Naldi, Luigi (2019). PRURITUS CHARACTERISTICS IN A LARGE ITALIAN COHORT OF PSORIATIC PATIENTS. Journal of the European Academy of Dermatology and Venereology : JEADV, 33(7), pp. 1316-1324. Wiley 10.1111/jdv.15539
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Background
Psoriasis (Ps) is a chronic systemic autoimmune disease associated with pruritus in 64-98% of patients. However, few modestly sized studies assess factors associated with psoriatic pruritus.
Objective
To investigate factors associated with Ps pruritus intensity.
Methods
Psoriasis patients 18 years or older seen in one of 155 centers in Italy between September 2005 and 2009 were identified from the Italian PsoCare registry. Patients without cutaneous psoriasis and those with missed information on pruritus were excluded.
Results
We identified 10,802 patients, with a mean age 48.8±14.3 years. Mild itch was present in 33.2% of patients, moderate in 34.4%, severe in 18.7% and very severe in 13.7%. Higher itch intensity was associated with female gender, lower educational attainment compared to university degree, pustular psoriasis, psoriasis on the head, face, palmoplantar areas, folds and genitalia, more severe disease, disease duration <15 years, and no or few prior systemic treatments.
Limitations
Effects of specific medication on itch were not assessed.
Conclusions
Pruritus should be evaluated during psoriasis visits, and physicians should be aware of patients at higher risk for itch. Further studies are needed to assess the effects of medications on itch, and establish therapy for psoriasis patients with persistent itch.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology |
UniBE Contributor: |
Cazzaniga, Simone |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1468-3083 |
Publisher: |
Wiley |
Language: |
English |
Submitter: |
Andrea Studer-Gauch |
Date Deposited: |
30 Dec 2019 09:06 |
Last Modified: |
05 Dec 2022 15:33 |
Publisher DOI: |
10.1111/jdv.15539 |
PubMed ID: |
31736536 |
Uncontrolled Keywords: |
education itch pruritus psoriasis pustular psoriasis treatment |
BORIS DOI: |
10.7892/boris.136791 |
URI: |
https://boris.unibe.ch/id/eprint/136791 |
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