[Ketogenic Diet and its Evidence-Based Therapeutic Implementation in Endocrine Diseases].

Stocker, Rahel Kristina; Reber Aubry, Emilie; Bally, Lilly; Nuoffer, Jean-Marc; Stanga, Zeno (2019). [Ketogenic Diet and its Evidence-Based Therapeutic Implementation in Endocrine Diseases]. Praxis, 108(8), pp. 541-553. Hogrefe 10.1024/1661-8157/a003246

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Ketogenic Diet and its Evidence-Based Therapeutic Implementation in Endocrine Diseases Abstract. Abstract: The ketogenic diet (KD) is a high-fat and very low-carb diet, which has been used primarily for treatment of therapy-resistant epilepsy in children. Implementation of the KD in other target populations is increasingly being discussed. This literature review provides first indications for a clinical benefit of the KD in diabetes mellitus type 2 (T2DM) and polycystic ovarian syndrome (PCOS). In many analysed studies, KD led to significant weight loss and had beneficial effects on lipoprotein profile and insulin resistance. In half of the comparative studies with T2DM, the KD lead to signifiantly greater reductions in HbA1c-levels (HbA1c difference: -0.5 to -1.5 %) compared to reference diets (HbA1c difference: +0.2 to -0.5 %). Nevertheless, study results are too heterogenic for a general recommendation of the KD in this patient population.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Endocrinology, Diabetology and Clinical Nutrition
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Institute of Clinical Chemistry

UniBE Contributor:

Aubry, Emilie; Bally, Lia Claudia; Nuoffer, Jean-Marc and Stanga-Nodari, Zeno

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1661-8157

Publisher:

Hogrefe

Language:

German

Submitter:

Alexandra Müller

Date Deposited:

30 Dec 2019 14:32

Last Modified:

09 Jan 2020 11:16

Publisher DOI:

10.1024/1661-8157/a003246

PubMed ID:

31185843

Uncontrolled Keywords:

Diabetes mellitus Typ 2 Ketogene Diät Ketogenic diet Régime cétogène diabète mellitus type 2 polycystic ovary syndrome (PCOS) polyzystisches Ovarialsyndrom (PCOS) syndrome des ovaires type 2 diabetes mellitus

BORIS DOI:

10.7892/boris.136888

URI:

https://boris.unibe.ch/id/eprint/136888

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