Statistical modeling of the eye for multimodal treatment planning for external beam radiation therapy of intraocular tumors

Rüegsegger, Michael B; Bach Cuadra, Meritxell; Pica, Alessia; Amstutz, Christoph A; Rudolph, Tobias; Aebersold, Daniel; Kowal, Jens H (2012). Statistical modeling of the eye for multimodal treatment planning for external beam radiation therapy of intraocular tumors. International journal of radiation oncology, biology, physics, 84(4), e541-7. New York, N.Y.: Elsevier 10.1016/j.ijrobp.2012.05.040

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Ocular anatomy and radiation-associated toxicities provide unique challenges for external beam radiation therapy. For treatment planning, precise modeling of organs at risk and tumor volume are crucial. Development of a precise eye model and automatic adaptation of this model to patients' anatomy remain problematic because of organ shape variability. This work introduces the application of a 3-dimensional (3D) statistical shape model as a novel method for precise eye modeling for external beam radiation therapy of intraocular tumors.

Item Type:	Journal Article (Original Article)
Division/Institute:	04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology 04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Radiation Oncology 10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research > ARTORG Center - AI in Medical Imaging Laboratory
UniBE Contributor:	Rüegsegger, Michael, Pica, Alessia, Rudolph, Tobias, Aebersold, Daniel Matthias, Kowal, Horst Jens
ISSN:	0360-3016
Publisher:	Elsevier
Language:	English
Submitter:	Factscience Import
Date Deposited:	04 Oct 2013 14:34
Last Modified:	02 Mar 2023 23:21
Publisher DOI:	10.1016/j.ijrobp.2012.05.040
PubMed ID:	22867896
Web of Science ID:	000310565300013
URI:	https://boris.unibe.ch/id/eprint/13693 (FactScience: 220290)