Statistical modeling of the eye for multimodal treatment planning for external beam radiation therapy of intraocular tumors

Rüegsegger, Michael B; Bach Cuadra, Meritxell; Pica, Alessia; Amstutz, Christoph A; Rudolph, Tobias; Aebersold, Daniel; Kowal, Jens H (2012). Statistical modeling of the eye for multimodal treatment planning for external beam radiation therapy of intraocular tumors. International journal of radiation oncology, biology, physics, 84(4), e541-7. New York, N.Y.: Elsevier 10.1016/j.ijrobp.2012.05.040

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Ocular anatomy and radiation-associated toxicities provide unique challenges for external beam radiation therapy. For treatment planning, precise modeling of organs at risk and tumor volume are crucial. Development of a precise eye model and automatic adaptation of this model to patients' anatomy remain problematic because of organ shape variability. This work introduces the application of a 3-dimensional (3D) statistical shape model as a novel method for precise eye modeling for external beam radiation therapy of intraocular tumors.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Radiation Oncology
10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research > ARTORG Center - Image Guided Therapy > ARTORG Center - Ophthalmic Technology Lab

UniBE Contributor:

Rüegsegger, Michael; Pica, Alessia; Rudolph, Tobias; Aebersold, Daniel and Kowal, Horst Jens

ISSN:

0360-3016

Publisher:

Elsevier

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:34

Last Modified:

06 Dec 2013 13:35

Publisher DOI:

10.1016/j.ijrobp.2012.05.040

PubMed ID:

22867896

Web of Science ID:

000310565300013

URI:

https://boris.unibe.ch/id/eprint/13693 (FactScience: 220290)

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