Management of Refeeding Syndrome in Medical Inpatients

Reber, Emilie; Friedli, Natalie; Vasiloglou, Maria; Schuetz, Philipp; Stanga, Zeno (2019). Management of Refeeding Syndrome in Medical Inpatients. Journal of clinical medicine, 8(12) MDPI 10.3390/jcm8122202

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Refeeding syndrome (RFS) is the metabolic response to the switch from starvation to a fed state in the initial phase of nutritional therapy in patients who are severely malnourished or metabolically stressed due to severe illness. It is characterized by increased serum glucose, electrolyte disturbances (particularly hypophosphatemia, hypokalemia, and hypomagnesemia), vitamin depletion (especially vitamin B1 thiamine), fluid imbalance, and salt retention, with resulting impaired organ function and cardiac arrhythmias. The awareness of the medical and nursing staff is often too low in clinical practice, leading to under-diagnosis of this complication, which often has an unspecific clinical presentation. This review provides important insights into the RFS, practical recommendations for the management of RFS in the medical inpatient population (excluding eating disorders) based on consensus opinion and on current evidence from clinical studies, including risk stratification, prevention, diagnosis, and management and monitoring of nutritional and fluid therapy.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Endocrinology, Diabetology and Clinical Nutrition
10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research > ARTORG Center - Diabetes Technology

Graduate School:

Graduate School for Cellular and Biomedical Sciences (GCB)

UniBE Contributor:

Vasiloglou, Maria and Stanga-Nodari, Zeno

Subjects:

600 Technology > 610 Medicine & health

ISSN:

2077-0383

Publisher:

MDPI

Language:

English

Submitter:

Stavroula Mougiakakou

Date Deposited:

13 Jan 2020 16:30

Last Modified:

13 Jan 2020 16:39

Publisher DOI:

10.3390/jcm8122202

PubMed ID:

31847205

BORIS DOI:

10.7892/boris.137098

URI:

https://boris.unibe.ch/id/eprint/137098

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