Current knowledge in pathophysiology and management of Budd-Chiari syndrome and non-cirrhotic non-tumoral splanchnic vein thrombosis.

Hernández-Gea, Virginia; De Gottardi, Andrea; Leebeek, Frank W G; Rautou, Pierre-Emmanuel; Salem, Riad; Garcia-Pagan, Juan Carlos (2019). Current knowledge in pathophysiology and management of Budd-Chiari syndrome and non-cirrhotic non-tumoral splanchnic vein thrombosis. Journal of hepatology, 71(1), pp. 175-199. Elsevier 10.1016/j.jhep.2019.02.015

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Budd-Chiari syndrome and non-cirrhotic non-tumoral portal vein thrombosis are 2 rare disorders, with several similarities that are categorized under the term splanchnic vein thrombosis. Both disorders are frequently associated with an underlying prothrombotic disorder. They can cause severe portal hypertension and usually affect young patients, negatively influencing life expectancy when the diagnosis and treatment are not performed at an early stage. Yet, they have specific features that require individual consideration. The current review will focus on the available knowledge on pathophysiology, diagnosis and management of both entities.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Hepatology
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie

UniBE Contributor:

De Gottardi, Andrea

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0168-8278

Publisher:

Elsevier

Language:

English

Submitter:

Thi Thao Anh Pham

Date Deposited:

17 Jan 2020 15:11

Last Modified:

17 Jan 2020 15:11

Publisher DOI:

10.1016/j.jhep.2019.02.015

PubMed ID:

30822449

Uncontrolled Keywords:

Angioplasty Coagulopathy Portal hypertension Portal vein thrombosis TIPS Thrombophilia Transplant

BORIS DOI:

10.7892/boris.137313

URI:

https://boris.unibe.ch/id/eprint/137313

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