Lung function, obesity and physical fitness in young children: The EXAMIN YOUTH study.

Köchli, Sabrina; Endes, Katharina; Bartenstein, Tim; Usemann, Jakob; Schmidt-Trucksäss, Arno; Frey, Urs; Zahner, Lukas; Hanssen, Henner (2019). Lung function, obesity and physical fitness in young children: The EXAMIN YOUTH study. Respiratory medicine, 159, p. 105813. Elsevier 10.1016/j.rmed.2019.105813

[img] Text
lung function, obesity and physical fitness in young children The EXAMIN YOUTH study_2019.pdf - Published Version
Restricted to registered users only
Available under License Publisher holds Copyright.

Download (533kB)

OBJECTIVE

The prevalence of obesity and physical inactivity in children are increasing globally. The study aimed to investigate the association of obesity and cardiorespiratory fitness (CRF) with patterns of lung function in young children.

METHODS

In this cross-sectional study, lung function, body mass index (BMI), blood pressure (BP) and CRF (shuttle run stages) were measured in an unselected cohort of 1246 children aged 7.2 ± 0.4 years. All parameters and lung function, such as the ratio of forced expiratory volume in 1 s (FEV1) to forced vital capacity (FVC), were assessed by standardized procedures for children. Statistical models were applied for systematic adjustment of potential confounders.

RESULTS

Obese children had significantly higher FEV1 (Coef. (95% CI) (1.57 (1.50; 1.64) L) and FVC (1.75 (1.67; 1.83) L) compared to normal weight children (1.38 (1.37; 1.40) L; (1.53 (1.51; 1.54) L, respectively). However, with each unit increase of BMI, FEV1/FVC decreased (-0.003 (-0.005; -0.001)) due to a disproportional increase in FVC compared to FEV1. Per stage increase of CRF, FEV1 (0.017 (0.008; 0.025) L) and FVC increased (0.022 (0.012; 0.031) L)). In obese children, higher CRF was independently associated with higher FEV1/FVC (0.03 (0.5E-4; 0.06)) due to a higher increase of FEV1 over FVC with increasing fitness.

CONCLUSIONS

The decrease of FEV1/FVC with increasing BMI suggests that childhood obesity is associated with an imbalance of ventilation and airway flow. In children with obesity, higher CRF is associated with an improved FEV1/FVC ratio. Physical exercise programs may have the potential to improve patterns of lung function in children with obesity.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > Unit Childrens Hospital > Forschungsgruppe Pneumologie (Pädiatrie)
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > Unit Childrens Hospital
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine > Paediatric Pneumology

UniBE Contributor:

Usemann, Jakob

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0954-6111

Publisher:

Elsevier

Language:

English

Submitter:

Anette van Dorland

Date Deposited:

24 Jan 2020 14:46

Last Modified:

05 Dec 2022 15:34

Publisher DOI:

10.1016/j.rmed.2019.105813

PubMed ID:

31731085

Uncontrolled Keywords:

Blood pressure Body mass index Cardiorespiratory fitness Pulmonary function

BORIS DOI:

10.7892/boris.137491

URI:

https://boris.unibe.ch/id/eprint/137491

Actions (login required)

Edit item Edit item
Provide Feedback