Differential item functioning of the Arm function in Multiple Sclerosis Questionnaire (AMSQ) by language, a study in six countries.

Kalkers, Nynke F; Galan, Ingrid; Kerbrat, Anne; Tacchino, Andrea; Kamm, Christian P.; O'Connell, Karen; McGuigan, Chris; Edan, Gilles; Montalban, Xavier; Uitdehaag, Bernard Mj; Mokkink, Lidwine B (2021). Differential item functioning of the Arm function in Multiple Sclerosis Questionnaire (AMSQ) by language, a study in six countries. Multiple sclerosis journal, 27(1), pp. 90-96. Sage 10.1177/1352458519895450

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BACKGROUND

The Arm function in Multiple Sclerosis Questionnaire (AMSQ) has been developed as a self-reported measure of arm and hand functioning for patients with multiple sclerosis (MS). The AMSQ was originally developed in Dutch and to date translated into five languages (i.e. English, German, Spanish, French, and Italian).

OBJECTIVE

The aim of this study was to evaluate differential item functioning (DIF) of the AMSQ in these languages.

METHODS

We performed DIF analyses, using "language" as the polytomous group variable. To detect DIF, logistic regression and item response theory principles were applied. Multiple logistic regression models were evaluated. We used a pseudo R2 value of 0.02 or more as the DIF threshold.

RESULTS

A total of 1733 male and female patients with all subtypes of MS were included. The DIF analysis for the whole dataset showed no uniform or non-uniform DIF on any of the 31 items. All R2 values were below 0.02.

CONCLUSION

The AMSQ is validated in six languages. All items have the same meaning to MS patients in Dutch, English, German, Spanish, French, and Italian. This validation study enables use of the AMSQ in international studies, for monitoring treatment response and disease progression.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology

UniBE Contributor:

Kamm, Christian Philipp

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1352-4585

Publisher:

Sage

Language:

English

Submitter:

Chantal Kottler

Date Deposited:

20 Jan 2020 13:00

Last Modified:

06 Jan 2021 01:30

Publisher DOI:

10.1177/1352458519895450

PubMed ID:

31845614

Uncontrolled Keywords:

Multiple sclerosis arm function differential item functioning hand function item response theory patient-reported outcome measure questionnaire upper extremity function

BORIS DOI:

10.7892/boris.137734

URI:

https://boris.unibe.ch/id/eprint/137734

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