Galli, Silvio; Aybek, Selma; Chokron, Sylvie; Moulin, Thierry; Magnin, Eloi (2019). Modification of both functional neurological symptoms and neuroimaging patterns with a good anatomoclinical concordance: a case report. BMC neurology, 19(1), p. 270. BioMed Central 10.1186/s12883-019-1475-3
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Galli, 2019, Modification of both funcitonal neurological symptoms.pdf - Published Version Available under License Creative Commons: Attribution (CC-BY). Download (2MB) | Preview |
BACKGROUND
In the nineteenth century, Jean Martin Charcot explained functional neurological disorder (formerly called conversion disorder) as a "psychodynamic" lesion. Numerous advances in neuroimaging have permitted identification of the neural underpinnings of this disorder.
CASE PRESENTATION
Herein we describe a case of functional neurological disorder (FND) with initial left sensorimotor deficit, in-coordinated limb movements, neglect, clouded consciousness, slurred speech and a semiology of visual impairment. A single photon emission computed tomography (SPECT) showed a right thalamic hypoperfusion, which is rather concordant with the initial semiology. Later, the semiology changed, presenting with a predominantly neurovisual complex presentation. The second SPECT showed no more thalamic abnormalities but an hypoperfusion in the right temporo-occipital junction, right inferior parietal lobe and left superior frontal lobe, which is also rather concordant with the changing semiology.
CONCLUSIONS
This case illustrates the evolving neuroimaging patterns of FND but also the concordance between semiology and neuroimaging findings in FND supporting Charcot's theory of "dynamic lesion".
Item Type: |
Journal Article (Further Contribution) |
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Division/Institute: |
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology |
UniBE Contributor: |
Aybek Rusca, Selma |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1471-2377 |
Publisher: |
BioMed Central |
Language: |
English |
Submitter: |
Chantal Kottler |
Date Deposited: |
08 Jan 2020 09:33 |
Last Modified: |
02 Mar 2023 23:32 |
Publisher DOI: |
10.1186/s12883-019-1475-3 |
PubMed ID: |
31684891 |
Uncontrolled Keywords: |
Conversion disorders Dissociative disorders Functional neurological disorders SPECT |
BORIS DOI: |
10.7892/boris.137737 |
URI: |
https://boris.unibe.ch/id/eprint/137737 |