Framing multiple sclerosis under a polysomnographic perspective.

Tanioka, Kosuke; Castelnovo, Anna; Tachibana, Naoko; Miano, Silvia; Zecca, Chiara; Gobbi, Claudio; Manconi, Mauro (2020). Framing multiple sclerosis under a polysomnographic perspective. Sleep, 43(3) Oxford University Press 10.1093/sleep/zsz232

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Multiple sclerosis (MS) is a mainly demyelinating, autoimmune, and disabling neurological disease. In addition to well-known clinically evident symptoms such as coordination or motor problems, increasing attention has been posed to a constellation of less evident symptoms significantly contributing to the clinical impact of MS. Among others, sleep symptoms have been only recently explored. This systematic review summarizes objective sleep findings detected by using polysomnography and their relationship with clinical variables in MS patients. While it is well known that sleep disorders are frequent in MS, objective clinical data are still scarce. Literature based on subjective reports indicate sleep disorders as highly frequent in MS patients; however, objective data are still scarce. New large case-control instrumental investigations are warranted to establish the real objective entity and impact of sleep comorbidities.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology

UniBE Contributor:

Manconi, Mauro

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1550-9109

Publisher:

Oxford University Press

Language:

English

Submitter:

Chantal Kottler

Date Deposited:

15 Jan 2020 13:07

Last Modified:

13 Mar 2020 01:32

Publisher DOI:

10.1093/sleep/zsz232

PubMed ID:

31637431

Uncontrolled Keywords:

AHI PLM PSG RLS apneas multiple sclerosis periodic leg movements restless leg syndrome sleep sleep architecture

BORIS DOI:

10.7892/boris.137739

URI:

https://boris.unibe.ch/id/eprint/137739

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