de Almeida Barros Mourão, Carlos Fernando; Miron, Richard J.; de Mello Machado, Rafael Coutinho; Ghanaati, Shahram; Alves, Gutemberg Gomes; Calasans-Maia, Mônica Diuana (2019). Usefulness of platelet-rich fibrin as a hemostatic agent after dental extractions in patients receiving anticoagulant therapy with factor Xa inhibitors: a case series. Oral and maxillofacial surgery, 23(3), pp. 381-386. Springer-Verlag 10.1007/s10006-019-00769-y
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DeAlmeidaBarrosMourão2019_Article_UsefulnessOfPlatelet-richFibri.pdf - Published Version Available under License Publisher holds Copyright. Download (668kB) | Preview |
PURPOSE
To evaluate the clinical outcomes of platelet-rich fibrin (PRF) application for hemostasis after dental extraction in patients receiving anticoagulant therapy with factor Xa inhibitors.
METHODS
In total, 25 patients receiving anticoagulant therapy with rivaroxaban or apixaban who required routine dental extraction were evaluated. In all patients, PRF was used for hemostasis in addition to adapting sutures. Bleeding was subjectively assessed using a sterilize gauze pad at 24, 48, and 72 h after the procedure.
RESULTS
All invited participants (n = 25) consented to participate. The PRF clots successfully arrested bleeding after extraction in all patients, with no complications at any time point after the procedure. Favorable soft tissue healing was observed during suture removal at 10 days after the procedure in all patients, with no signs of infection or late healing.
CONCLUSIONS
The results of this case series indicate that PRF is a promising natural hemostatic agent for the management of bleeding after dental extraction in patients receiving factor Xa inhibitor therapy. Further controlled clinical studies with larger patient samples are necessary to clarify the findings of this case series.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > School of Dental Medicine > Department of Periodontology 04 Faculty of Medicine > School of Dental Medicine > Periodontics Research |
UniBE Contributor: |
Miron, Richard John |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1865-1550 |
Publisher: |
Springer-Verlag |
Language: |
English |
Submitter: |
Doris Burri |
Date Deposited: |
20 Jan 2020 10:54 |
Last Modified: |
19 May 2023 00:25 |
Publisher DOI: |
10.1007/s10006-019-00769-y |
PubMed ID: |
31102080 |
Uncontrolled Keywords: |
Anticoagulant therapy Clot stability Dental extraction Hemostasis Platelet-rich fibrin |
BORIS DOI: |
10.7892/boris.137814 |
URI: |
https://boris.unibe.ch/id/eprint/137814 |
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