An evidence-based analysis of the management of N0 neck in patients with cancer of the parotid gland.

Vartanian, Jose Guilherme; Gonçalves Filho, Joao; Kowalski, Luiz Paulo; Shah, Jatin P; Suárez, Carlos; Rinaldo, Alessandra; De Bree, Remco; Rodrigo, Juan P; Hamoir, Marc; Takes, Robert P; Mäkitie, Antti A; Zbären, Peter; Andreasen, Simon; Poorten, Vincent Vander; Sanabria, Alvaro; Hellquist, Henrik; Robbins, K Thomas; Bödeker, Carsten C; Silver, Carl and Ferlito, Alfio (2019). An evidence-based analysis of the management of N0 neck in patients with cancer of the parotid gland. Expert review of anticancer therapy, 19(10), pp. 899-908. Taylor & Francis 10.1080/14737140.2019.1674143

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Introduction: Management of clinically negative neck (cN0) in patients with parotid gland cancer is controversial. Treatment options can include observation, elective neck dissection or elective radiotherapy. Areas covered: We addressed the treatment options for cN0 patients with parotid gland cancer. A literature review was undertaken to determine the optimal management of this group of patients. Expert opinion: Patients with parotid carcinoma and clinically negative neck have various options for their management. The analysis of tumor stage, histology and grade is essential to better define patients at risk for occult lymph node metastasis. These patients can be managed by surgery, radiotherapy or their combination, depending on the presence of risk factors, the moment at which such risk factors are detected, patient-related clinical conditions, medical provider expertise and institutional facilities.

Item Type:

Journal Article (Review Article)


04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ear, Nose and Throat Disorders (ENT)

UniBE Contributor:

Zbären, Peter


600 Technology > 610 Medicine & health




Taylor & Francis




Stefan Weder

Date Deposited:

22 Jan 2020 12:35

Last Modified:

22 Jan 2020 12:35

Publisher DOI:


PubMed ID:


Uncontrolled Keywords:

Salivary gland elective neck treatment neck dissection parotid gland radiotherapy


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