Millius, Nicolas; Lapointe, Guillaume; Renaud, Philippe (2019). Two-Step Azidoalkenylation of Terminal Alkenes Using Iodomethyl Sulfones. Molecules, 24(22), p. 4184. MDPI 10.3390/molecules24224184
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The radical azidoalkylation of alkenes that was initially developed with α-iodoesters and α-iodoketones was extended to other activated iodomethyl derivatives. By using iodomethyl aryl sulfones, the preparation of γ-azidosulfones was easily achieved. Facile conversion of these azidosulfones to homoallylic azides using a Julia–Kocienski olefination reaction is reported, making the whole process equivalent to the azidoalkenylation of terminal alkenes.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
08 Faculty of Science > Department of Chemistry, Biochemistry and Pharmaceutical Sciences (DCBP) |
UniBE Contributor: |
Renaud, Philippe |
Subjects: |
500 Science > 570 Life sciences; biology 500 Science > 540 Chemistry |
ISSN: |
1420-3049 |
Publisher: |
MDPI |
Language: |
English |
Submitter: |
Franziska Bornhauser-Rufer |
Date Deposited: |
06 Feb 2020 15:29 |
Last Modified: |
07 Aug 2024 15:45 |
Publisher DOI: |
10.3390/molecules24224184 |
BORIS DOI: |
10.7892/boris.138850 |
URI: |
https://boris.unibe.ch/id/eprint/138850 |
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