Evolutionary origins and impacts of genome architecture in ciliates.

Maurer-Alcalá, Xyrus X.; Nowacki, Mariusz (2019). Evolutionary origins and impacts of genome architecture in ciliates. Annals of the New York Academy of Sciences, 1447(1), pp. 110-118. New York Academy of Sciences 10.1111/nyas.14108

[img]
Preview
Text
Maurer-Alcal-_et_al-2019-Annals_of_the_New_York_Academy_of_Sciences.pdf - Published Version
Available under License Creative Commons: Attribution-Noncommercial (CC-BY-NC).

Download (454kB) | Preview

Genome architecture is well diversified among eukaryotes in terms of size and content, with many being radically shaped by ancient and ongoing genome conflicts with transposable elements (e.g., the large transposon-rich genomes common among plants). In ciliates, a group of microbial eukaryotes with distinct somatic and germ-line genomes present in a single cell, the consequences of these genome conflicts are most apparent in their developmentally programmed genome rearrangements. This complicated developmental phenomenon has largely overshadowed and outpaced our understanding of how germ-line and somatic genome architectures have influenced the evolutionary dynamism and potential in these taxa. In our review, we highlight three central concepts: how the evolution of atypical ciliate germ-line genome architectures is linked to ancient genome conflicts; how the complex, epigenetically guided transformation of germline to soma during development can generate widespread genetic variation; and how these features, coupled with their unusual life cycle, have increased the rate of molecular evolution linked to genome architecture in these taxa.

Item Type:

Journal Article (Review Article)

Division/Institute:

08 Faculty of Science > Department of Biology > Institute of Cell Biology > Ciliate
08 Faculty of Science > Department of Biology > Institute of Cell Biology

UniBE Contributor:

Maurer-Alcalá, Xyrus Xavier and Nowacki, Mariusz

Subjects:

500 Science > 570 Life sciences; biology

ISSN:

1749-6632

Publisher:

New York Academy of Sciences

Language:

English

Submitter:

Mariusz Nowacki

Date Deposited:

30 Jan 2020 11:16

Last Modified:

30 Jan 2020 11:16

Publisher DOI:

10.1111/nyas.14108

PubMed ID:

31074010

Uncontrolled Keywords:

ciliates evolution genome architecture genome evolution transposable elements

BORIS DOI:

10.7892/boris.139085

URI:

https://boris.unibe.ch/id/eprint/139085

Actions (login required)

Edit item Edit item
Provide Feedback