Kronenberg, A; Krähenbühl, S; Zimmermann, A; Streuli, R (1998). [Severe hepatocellular damage after administration of paracetamol and chlorzoxazone in therapeutic dosage]. Praxis - schweizerische Rundschau für Medizin, 87(41), pp. 1356-1360. Huber
Full text not available from this repository. (Request a copy)A 64 year old patient developed severe hepatocellular damage with jaundice and coagulopathy during ingestion of a combination of paracetamol and chlorzoxazone in therapeutic dosage. The risk factors for the development of liver cell necrosis following ingestion of paracetamol in therapeutic dosage are discussed. In particular in patients with risk factors (e.g. alcoholics and patients with heart failure) paracetamol-induced liver failure has to be considered in the presence of high transaminases, even when paracetamol was ingested in therapeutic dosage. Chlorzoxazone itself rarely can induce an idiosyncratic hepatocellular damage.
Item Type: |
Journal Article (Further Contribution) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Infectiology |
UniBE Contributor: |
Kronenberg, Andreas Oskar |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1661-8157 |
Publisher: |
Huber |
Language: |
German |
Submitter: |
Andreas Oskar Kronenberg |
Date Deposited: |
03 Feb 2021 09:56 |
Last Modified: |
05 Dec 2022 15:36 |
PubMed ID: |
9828666 |
URI: |
https://boris.unibe.ch/id/eprint/139178 |
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