Meta-analysis: Fixed-effect model

Spineli, Loukia M.; Pandis, Nikolaos (2020). Meta-analysis: Fixed-effect model. American journal of orthodontics and dentofacial orthopedics, 157(1), pp. 134-137. Elsevier 10.1016/j.ajodo.2019.10.008

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A meta-analysis, a statistical combination of data
from selected studies, is implemented by
choosing a priori between 2 popular statistical
models: fixed-effect and random-effects models.1 The
choice of the appropriate model for the analysis is critical
to ensure the credibility of the results and depends on
both the goals of the analysis and the assumptions of
the models.1 In this section, we introduce these 2
models, describe how to perform a meta-analysis under
these models, and apply a real-data example from a published
systematic review.

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